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Updated: May 13, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Endophthalmitis.

M L Durand1

  • 1Infectious Disease Service, Massachusetts Eye and Ear Infirmary, Boston, MA, USA. mdurand@partners.org

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
|February 27, 2013
PubMed
Summary
This summary is machine-generated.

Endophthalmitis is an urgent eye infection. Prompt treatment with intravitreal antibiotics and possibly vitrectomy can preserve vision in many cases.

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Area of Science:

  • Ophthalmology
  • Infectious Diseases

Background:

  • Endophthalmitis is an infection within the eye's internal fluid-filled chambers.
  • It can result from surgery, trauma, corneal infections, or spread from elsewhere in the body.

Purpose of the Study:

  • To review the causes, pathogens, and management of endophthalmitis.

Main Methods:

  • Literature review of endophthalmitis causes, pathogens, and treatment strategies.

Main Results:

  • Common causes include post-surgical, post-traumatic, and post-injection infections.
  • Pathogens vary by cause: Staphylococci (post-cataract), Bacillus cereus (post-trauma), Klebsiella pneumoniae (endogenous in East Asia), Candida (fungal).
  • Treatment involves intravitreal antibiotics and potentially vitrectomy; systemic antibiotics are used for endogenous and fungal cases.

Conclusions:

  • Acute endophthalmitis requires immediate intervention.
  • Effective treatment, including intravitreal antibiotics, can lead to vision recovery.