Related Experiment Video
Updated: May 13, 2026

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Prevalence of macular anatomic abnormalities in high myopia
Andrée Henaine-Berra1, Igal M Zand-Hadas, Jans Fromow-Guerra
1Retina Department, Asociación Para Evitar la Ceguera en México IAP, Hospital Dr. Luis Sánchez Bulnes, Mexico City, Mexico. a_h_b@hotmail.com
Background And Objective:
Macular anatomic abnormalities in high myopia are more frequent in the presence of posterior staphyloma. The objective was to determine the prevalence of foveoschisis, foveal detachment, vascular traction, epiretinal membrane (ERM), and macular hole (MH) in eyes with high myopia by spectral-domain optical coherence tomography.
Patients And Methods:
Prospective, observational study. Eyes with myopia greater than 8 diopters (D) were included. Results were analyzed using chi-square and Student's t tests.
Results:
The study included 116 eyes of 72 patients. Mean spherical equivalent: -15.04 ± 5.33 D. Mean axial length: 28.88 ± 2.31 mm. Foveoschisis was observed in 17 eyes (14.65%), vascular traction in 17 (14.65%), ERM in 13 (11.2%), lamellar MH in two (1.72%), and posterior staphyloma in 41 (35.34%). Presence of foveoschisis, vascular traction, and ERM was more frequent in eyes with posterior staphyloma (P = .0001).
Conclusion:
Macular anatomic abnormalities were observed in 22.41% of eyes with high myopia and in 53.65% of eyes with posterior staphyloma.
Related Concept Videos
Focusing of Light in the Eye
Glaucoma: Overview

