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Meiosis vs. Mitosis

Meiosis vs. Mitosis

Cell division is necessary for growth and reproduction in organisms. Mitosis aids cell growth and development by dividing somatic cells. In contrast, meiosis causes the division of germ cells and plays an essential role in sexual reproduction. Due to their unique functional requirements, mitosis and meiosis differ from each other in multiple aspects.
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...

Meiosis vs. Mitosis

Meiosis vs. Mitosis

Cell division is necessary for growth and reproduction in organisms. Mitosis aids cell growth and development by dividing somatic cells. In contrast, meiosis causes the division of germ cells and plays an essential role in sexual reproduction. Due to their unique functional requirements, mitosis and meiosis differ from each other in multiple aspects.
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...

Crossing Over

Crossing Over

Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I, where each chromosome—replicated in S phase—is now composed of two sister chromatids (identical copies) joined centrally.
The homologous pairs of sister chromosomes—one from the maternal and one from the paternal genome—then begin to align alongside each other lengthwise, matching corresponding DNA positions in a process called synapsis.
In order to...

Mitosis and Cytokinesis

Mitosis and Cytokinesis

In eukaryotes, the cell division cycle is divided into distinct, coordinated cellular processes that include cell growth, DNA replication/chromosome duplication, chromosome distribution to daughter cells, and finally, cell division. The cell cycle is tightly regulated by its regulatory systems as well as extracellular signals that affect cell proliferation.
The processes of the cell cycle occur over approximately 24 hours (in typical human cells) and in two major distinguishable stages. The...

Mitosis and Cytokinesis

Mitosis and Cytokinesis

In eukaryotes, the cell division cycle is divided into distinct, coordinated cellular processes that include cell growth, DNA replication/chromosome duplication, chromosome distribution to daughter cells, and finally, cell division. The cell cycle is tightly regulated by its regulatory systems as well as extracellular signals that affect cell proliferation.
The processes of the cell cycle occur over approximately 24 hours (in typical human cells) and in two major distinguishable stages. The...

Mitosis and Cytokinesis

Mitosis and Cytokinesis

In eukaryotes, the cell division cycle is divided into distinct, coordinated cellular processes that include cell growth, DNA replication/chromosome duplication, chromosome distribution to daughter cells, and finally, cell division. The cell cycle is tightly regulated by its regulatory systems as well as extracellular signals that affect cell proliferation.
The processes of the cell cycle occur over approximately 24 hours (in typical human cells) and in two major distinguishable stages. The...

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Related Experiment Video

Updated: May 13, 2026

Live Cell Imaging to Assess the Dynamics of Metaphase Timing and Cell Fate Following Mitotic Spindle Perturbations

Live Cell Imaging to Assess the Dynamics of Metaphase Timing and Cell Fate Following Mitotic Spindle Perturbations

Published on: September 20, 2019

Rheostat-ing mitosis.

Patrick A Eyers¹

¹Department of Oncology, CR-UK/YCR Sheffield Cancer Research Centre, University of Sheffield, Sheffield S10 2RX, UK. p.eyers@sheffield.ac.uk

Chemistry & Biology

|February 27, 2013

Summary

This summary is machine-generated.

Researchers discovered a novel inhibitor for Ark1, a key protein regulating cell division in yeast. This new compound helps scientists study the precise effects of Ark1 signaling during mitosis.

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Examination of Mitotic and Meiotic Fission Yeast Nuclear Dynamics by Fluorescence Live-cell Microscopy

Published on: June 24, 2019

Related Experiment Videos

Last Updated: May 13, 2026

Live Cell Imaging to Assess the Dynamics of Metaphase Timing and Cell Fate Following Mitotic Spindle Perturbations

Live Cell Imaging to Assess the Dynamics of Metaphase Timing and Cell Fate Following Mitotic Spindle Perturbations

Published on: September 20, 2019

Studying Proteolysis of Cyclin B at the Single Cell Level in Whole Cell Populations

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Published on: September 17, 2012

Examination of Mitotic and Meiotic Fission Yeast Nuclear Dynamics by Fluorescence Live-cell Microscopy

Examination of Mitotic and Meiotic Fission Yeast Nuclear Dynamics by Fluorescence Live-cell Microscopy

Published on: June 24, 2019

Area of Science:

Molecular Biology
Cell Biology
Biochemistry

Background:

Aurora kinases are crucial regulators of mitosis across eukaryotes.
Ark1 is the sole Aurora kinase in the fission yeast Schizosaccharomyces pombe, controlling diverse mitotic events.
Understanding Ark1 function is vital for comprehending cell cycle regulation.

Discussion:

Kawashima and colleagues have identified and validated a specific inhibitor for fungal Ark1.
This inhibitor allows for the targeted investigation of endogenous Ark1 signaling pathways.
The study provides a chemical tool to dissect the roles of Ark1 in mitotic progression.

Key Insights:

Discovery of a novel, validated Ark1 inhibitor specific to fungi.
Demonstration of the inhibitor's utility in evaluating mitotic outputs of Ark1.
Provides a new avenue for studying Aurora kinase function in cell division.

Outlook:

The identified inhibitor could serve as a lead compound for developing broader antifungal or antimitotic agents.
Further research can utilize this tool to explore conserved functions of Aurora kinases in other organisms.
This work opens possibilities for targeted therapies exploiting mitotic regulation.