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Updated: May 13, 2026

Monitoring the Mechanical Evolution of Tissue During Neural Tube Closure of Chick Embryo
Published on: November 10, 2023
Gender and associated skeletal abnormalities in fetuses with neural tube defects
Tanya Todorova Kitova1, Emilia Karaslavova, Soumeya Siala Gaigi
1Medical University of Plovdiv, Bulgaria. tanyakitova@yahoo.com
Objective:
To determine the association between gender and skeletal defects in fetuses with NTDs.
Methods:
150 NTD fetuses have been examined in three years' course (01.2006-01.2009) in the Clinic of Fetopathology at the Center for Maternity and Neonatology, Tunis.
Results:
The most common gender associated anomalies for males are cleft palate, anomalies in the form and attachment of the outer ear and the agenesis of corpus callosum. For women, they are distortions of the spine and "frog" face.
Conclusion:
The proven associations in the study are important indicators in the purposeful search for NTDs in early prenatal ultrasound diagnosis.
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