Related Experiment Video
Updated: May 13, 2026

Encapsulation of Cancer Therapeutic Agent Dacarbazine Using Nanostructured Lipid Carrier
Published on: April 26, 2016
Ultra-small NLC for improved dermal delivery of coenyzme Q10
Julia C Schwarz1, Nuttakorn Baisaeng, Magdalena Hoppel
1University of Vienna, Research Platform Characterisation of Drug Delivery Systems on Skin and Investigation of Involved Mechanisms, Althanstraße 14, 1090 Vienna, Austria. julia.schwarz@univie.ac.at
Abstract:
Coenzyme Q10 (CoQ10) acts as an antioxidant in the skin and is frequently contained in anti-aging products. In previous studies, it could be shown that nano-structured lipid carriers (NLC) with a size of about 230 nm are beneficial for the dermal delivery of CoQ10. They increased Q10 skin penetration when compared to equally sized nanoemulsion. In this study, ultra-small NLC were prepared with even smaller mean particles sizes of around 80 nm. The influence of this decrease of particle size was investigated in terms of skin permeation and penetration as well as physicochemical stability of the NLC. Improved dermal delivery of CoQ10 by ultra-small NLC could be achieved.
More Related Videos
Related Concept Videos
Transdermal Drug Delivery Systems
Modified-Release Drug Delivery Systems: Site-Targeted
Bioavailability Enhancement: Drug Permeability Enhancement
Drug Delivery: Overview
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the gastrointestinal...
Modified-Release Drug Delivery Systems: Bioavailability
Modified-Release Drug Delivery Systems: Rate-Programmed II

