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Related Concept Videos

Antidepressant Drugs: Overview01:25

Antidepressant Drugs: Overview

Antidepressant drugs are a class of medications primarily used for treating various mood disorders, including major depression, anxiety disorders, and other related conditions. These medicines work by modulating the neurotransmitter balance within the brain, alleviating depressive symptoms. Antidepressants can be broadly categorized into several groups according to their mechanism of action and chemical structure: Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin-Norepinephrine...
Antidepressant Drugs: MAOIs and Other Agents01:23

Antidepressant Drugs: MAOIs and Other Agents

Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs01:28

Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs

Tricyclic Antidepressants (TCAs), including Desipramine (Norpramin), Imipramine (Tofranil), Clomipramine (Anafranil), and Amitriptyline (Elavil), inhibit serotonin and norepinephrine reuptake and also block other receptors. They are used for depression, pain conditions, and insomnia. Common adverse effects include anticholinergic effects, sedation, orthostatic hypotension, and weight gain. They have a narrow therapeutic window and so require plasma-level monitoring. Abrupt discontinuation can...
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Therapeutic Drug Monitoring: Affecting Factors01:29

Therapeutic Drug Monitoring: Affecting Factors

Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
Mania and Antimanic Drugs: Overview01:24

Mania and Antimanic Drugs: Overview

Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as a...

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Related Experiment Video

Updated: May 13, 2026

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
08:15

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model

Published on: June 6, 2025

IPS multicentric study: Antidepressant prescription patterns.

Sandeep Grover1, Ajit Avasth, Kamal Kalita

  • 1Members of Indian Psychiatric Society, India.

Indian Journal of Psychiatry
|February 27, 2013
PubMed
Summary
This summary is machine-generated.

Escitalopram and selective serotonin reuptake inhibitors (SSRIs) are the most prescribed antidepressants in India for first-episode depression. Benzodiazepines are frequently used as co-prescriptions.

Keywords:
Antidepressantsdepressionprescriptions

Related Experiment Videos

Last Updated: May 13, 2026

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
08:15

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model

Published on: June 6, 2025

Area of Science:

  • Psychiatry
  • Pharmacology
  • Clinical Research

Background:

  • Limited studies from India evaluate antidepressant prescription patterns by psychiatrists for depression.
  • Understanding current prescribing practices is crucial for evidence-based treatment.

Purpose of the Study:

  • To investigate psychotropic prescription patterns for first-episode depression patients.
  • To analyze data from diverse settings, including public and private sectors and private psychiatric clinics.

Main Methods:

  • Evaluation of prescription data from 706 patients with first-episode depression.
  • Inclusion of data from a multicentric study (IPS).

Main Results:

  • Escitalopram was the most frequent antidepressant (40%), followed by sertraline (17.6%) and fluoxetine (16.3%).
  • Selective serotonin reuptake inhibitors (SSRIs) constituted 79.2% of all antidepressant prescriptions.
  • Benzodiazepines were prescribed to 74.1% of patients, with clonazepam being the most common.

Conclusions:

  • Escitalopram and SSRIs are the predominant antidepressant choices in India.
  • Concomitant antidepressant use (polypharmacy) is infrequent.
  • Benzodiazepine co-prescription is a common practice.