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Body surface area as a key determinant of aortic root and arch dimensions in a population-based study
Yan-Li Wang1, Qing-Ling Wang, Liang Wang
1Department of Cardiology, Shanghai East Hospital, Tongji University, Shanghai 200120; ; Department of Cardiology, Anyang People's Hospital, Anyang, Henan 455000, P.R. China ;
Insights
Body surface area is the best predictor of aortic dimensions in the Chinese population. This finding helps establish reference standards for aortic sinus, annulus, and arch measurements.
Area of Science:
- Cardiovascular Imaging
- Medical Ultrasound
- Population Health
Background:
- Aortic dimensions are crucial for cardiovascular health assessment.
- Limited data exists on aortic dimensions and their physiological correlates in the Chinese population.
- Understanding these associations is vital for accurate diagnosis and risk stratification.
Purpose of the Study:
- To investigate the associations between physiological variables and aortic dimensions (sinus, annulus, arch) in a Chinese cohort.
- To establish echocardiographic reference standards for aortic root and arch measurements.
- To identify key predictors of aortic dimensions in this population.
Main Methods:
- Cross-sectional study involving 1,010 Chinese subjects.
- Two-dimensional transthoracic echocardiography was used to measure aortic sinus, annulus, and arch diameters.
- Statistical analysis was performed using Epidata, Excel, and SPSS.
Main Results:
- Body surface area (BSA) was identified as the strongest predictor of aortic sinus, annulus, and arch dimensions (r=0.54, 0.37, 0.39, respectively).
- Gender, blood pressure, and age were also significant predictors.
- BSA demonstrated independent predictive value for all measured aortic dimensions.
Conclusions:
- Body surface area is the primary determinant of aortic dimensions in the Chinese population.
- These findings provide essential reference values for echocardiographic assessment of aortic structures.
- The study highlights the importance of BSA in evaluating aortic health in this demographic.
Abstract:
The associations between the aortic dimensions (of the aortic sinus, aortic annulus and aortic arch) and physiological variables have not been established in the Chinese population. The present study examined the associations among physiological variables to determine the aortic root and arch dimensions echocardiographically. The diameters of the aortic sinus, annulus and arch were measured in 1,010 subjects via 2-D echocardiography with a 3.5-MHz transducer in a trans-thoracic position. The images of the aortic sinus and aortic annulus were obtained from a standard parasternal long-axis view. The maximum diameter of the valve orifice was measured at the end of systole. The aortic arch dimension was visualized in the long-axis using a suprasternal notch window and the maximum transverse diameter was measured. Epidata 3.0, Excel 2007 and SPSS version 17.0 were used to collect and analyze the data. A total of 1,010 subjects were enrolled. The mean age was 55.0±17.0 years (range of 18 to 90 years). The body surface area (BSA) was the best predictor of all the studied physiological variables and may be used to predict aortic sinus, annulus and arch dimensions independently (r=0.54, 0.37 and 0.39, respectively). Gender, blood pressure, age and BSA are significant predictors of the aortic dimensions. Of these, BSA was the best predictor.
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