Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Predicting mortality risk in hospitalized ACS patients with hypertensive comorbidity: an interpretable machine learning approach.

BMC medical informatics and decision making·2026
Same author

Advancing ST-elevated myocardial infarction mortality risk prediction in Asian populations through explainable and calibrated machine learning.

Digital health·2026
Same author

Time to Ditch 'Diurese & Discharge'- Spotlight on Heart Failure in Malaysia.

Journal of geriatric cardiology : JGC·2026
Same author

Machine learning-based prediction of mortality risk from air pollution-induced acute coronary syndrome in the Western Pacific region.

Scientific reports·2026
Same author

Validation of the European Society of Cardiology 0/1-hour algorithm for chest pain triage in Asian emergency departments: a multinational stepped-wedge cluster-randomised trial.

Heart (British Cardiac Society)·2025
Same author

Non-Invasive Respiratory Support for Acute Cardiogenic Pulmonary Edema in the Acute Care Setting.

Current heart failure reports·2025

Related Experiment Video

Updated: May 13, 2026

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms
06:50

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms

Published on: September 16, 2022

Vulnerable plaque: from bench to bedside; local pacification versus systemic therapy.

Sazzli Kasim1, Darragh Moran, Eugene McFadden

  • 1Cardiology Unit, Medical Faculty, UiTM Sg Buloh, Selangor, Malaysia ; Division of Cardiology, Cork University Hospital, Cork, Ireland.

Heart Views : the Official Journal of the Gulf Heart Association
|February 27, 2013
PubMed
Summary

Most heart attacks stem from non-obstructive plaques, not critical stenoses. New imaging identifies vulnerable plaques, enabling targeted therapies to prevent sudden death and acute coronary syndromes.

Keywords:
Atherosclerosisinterventionpathogenesistreatmentvulnerable plaque

More Related Videos

Viral Concentration Determination Through Plaque Assays: Using Traditional and Novel Overlay Systems
09:28

Viral Concentration Determination Through Plaque Assays: Using Traditional and Novel Overlay Systems

Published on: November 4, 2014

Related Experiment Videos

Last Updated: May 13, 2026

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms
06:50

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms

Published on: September 16, 2022

Viral Concentration Determination Through Plaque Assays: Using Traditional and Novel Overlay Systems
09:28

Viral Concentration Determination Through Plaque Assays: Using Traditional and Novel Overlay Systems

Published on: November 4, 2014

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Medical Imaging

Background:

  • Acute coronary syndromes (ACS) and sudden cardiac death are often caused by coronary thromboses.
  • These thromboses frequently originate from atheromatous plaques not severe enough for angiographic detection.

Purpose of the Study:

  • To review past, present, and future therapeutic strategies for managing high-risk coronary lesions.
  • To highlight the role of noninvasive imaging in identifying vulnerable plaques.

Main Methods:

  • Literature review of therapeutic interventions for coronary artery disease.
  • Discussion of advancements in noninvasive plaque imaging techniques.
  • Analysis of the natural history of vulnerable plaque progression.

Main Results:

  • Critical coronary stenoses are a minor cause of ACS; most result from thromboses of non-obstructive atheroma.
  • Noninvasive imaging of vulnerable plaques offers new avenues for risk stratification and treatment.
  • Therapeutic approaches are evolving alongside our understanding of plaque biology.

Conclusions:

  • Identifying and treating vulnerable plaques is crucial for reducing ACS and sudden death.
  • Future therapies will likely focus on preventing plaque rupture and thrombosis.
  • Personalized treatment strategies based on plaque assessment are becoming increasingly important.