Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

Overview
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterisation of Allergen Profiles in Commercial Egg Products to Inform Oral Immunotherapy Strategies in Egg Allergy.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2026
Same author

Proteomic Mapping of Allergenic Proteins Reveals Key Differences Between Black Tiger Prawn (<i>Penaeus monodon</i>) and White Leg Prawn (<i>Litopenaeus vannamei</i>).

Journal of proteome research·2026
Same author

Proteomic Insights into the Immune and Sex-Specific Proteins in the Skin Mucus of Barramundi (<i>Lates calcarifer</i>).

Proteomes·2026
Same author

Thermal stress alters the allergen and proteome profile of the redclaw crayfish (Cheraxquadicarinatus).

Fish & shellfish immunology·2026
Same author

Fish size matters - Variable food allergen profiles in farmed and wild Malabar red snapper (Lutjanus malabaricus).

Food chemistry·2026
Same author

Quality of life is impaired in shrimp allergic adults and caregivers.

Frontiers in allergy·2025
Same journal

Therapeutic Targeting of the Bradykinin B2 Receptor in Immunological and Vascular Diseases: Insights from Kinin Biology to Clinical Outcomes.

Clinical reviews in allergy & immunology·2026
Same journal

β-blocker Therapy in Cholinergic Urticaria, Adrenergic Urticaria and the Aquagenic Continuum Beta-Blocker Therapy in Chronic Inducible Urticaria.

Clinical reviews in allergy & immunology·2026
Same journal

Immunopathogenesis and Cytokine Pathways in Reactive Infectious Mucocutaneous Eruption (RIME) in Pediatric Population: Infectious Triggers and Molecular Insights.

Clinical reviews in allergy & immunology·2026
Same journal

Neuropsychological Factors in Vitiligo: Mechanisms and Clinical Application.

Clinical reviews in allergy & immunology·2026
Same journal

Tertiary Lymphoid Structure: A Potential Therapeutic Target Affecting Immune Response in Autoimmune Diseases.

Clinical reviews in allergy & immunology·2026
Same journal

Differentiating Acute-onset Autoimmune Hepatitis From Drug-Induced Autoimmune-like Hepatitis: A Multicenter Study and Score Development.

Clinical reviews in allergy & immunology·2026
See all related articles

Related Experiment Video

Updated: May 13, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

Fish allergy: in review.

Michael F Sharp1, Andreas L Lopata

  • 1Molecular Immunology Group, Center of Biodiscovery and Molecular Development of Therapeutics, School of Pharmacy and Molecular Science, James Cook University, Townsville, Australia.

Clinical Reviews in Allergy & Immunology
|February 27, 2013
PubMed
Summary
This summary is machine-generated.

Fish allergy, a serious condition often outgrown by children, affects 0.2-2.29% of the population. This review covers new findings on fish allergy causes, diagnosis, and management.

More Related Videos

Humanized Mediator Release Assay as a Read-Out for Allergen Potency
10:22

Humanized Mediator Release Assay as a Read-Out for Allergen Potency

Published on: June 29, 2021

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

Related Experiment Videos

Last Updated: May 13, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

Humanized Mediator Release Assay as a Read-Out for Allergen Potency
10:22

Humanized Mediator Release Assay as a Read-Out for Allergen Potency

Published on: June 29, 2021

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

Area of Science:

  • Food science
  • Immunology
  • Public health

Background:

  • Rising fish consumption increases adverse reactions, including allergies, toxins, and parasites.
  • Fish allergy is a serious, potentially life-threatening condition that children typically do not outgrow.
  • Exposure routes include ingestion, handling, and inhalation of cooking vapors, affecting both domestic and occupational settings.

Purpose of the Study:

  • To review current knowledge on fish allergy, including demographics, novel allergens, and immunological mechanisms.
  • To discuss innovative diagnostic and management strategies for fish allergy.
  • To highlight the increasing prevalence and significance of fish allergy globally.

Main Methods:

  • Literature review of recent studies on fish allergy.
  • Analysis of epidemiological data on fish allergy prevalence.
  • Synthesis of information on allergen identification and immunological pathways.

Main Results:

  • Prevalence of self-reported fish allergy ranges from 0.2% to 2.29% in the general population, up to 8% in fish processing workers.
  • Parvalbumin is the major fish allergen, with other less common allergens also identified.
  • Fish allergy prevalence varies geographically and is influenced by dietary habits, processing methods, and specific fish species exposure.

Conclusions:

  • Fish allergy is a significant and persistent health concern with diverse triggers and exposure routes.
  • Further research into novel allergens and immunological mechanisms is crucial for improved diagnosis and management.
  • Innovative approaches are needed to address the lifelong nature and increasing prevalence of fish allergy.