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Related Concept Videos

Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
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Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Long-term Depression01:03

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
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Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
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Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
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Antidepressant drugs are a class of medications primarily used for treating various mood disorders, including major depression, anxiety disorders, and other related conditions. These medicines work by modulating the neurotransmitter balance within the brain, alleviating depressive symptoms. Antidepressants can be broadly categorized into several groups according to their mechanism of action and chemical structure: Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin-Norepinephrine...

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Related Experiment Video

Updated: May 13, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
04:33

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

IPS multicentric study: Functional somatic symptoms in depression.

Sandeep Grover1, Ajit Avasthi, Kamal Kalita

  • 1Members of Indian Psychiatric Society, India.

Indian Journal of Psychiatry
|February 27, 2013
PubMed
Summary
This summary is machine-generated.

Functional somatic symptoms are common in Indian patients with first episode depression. These symptoms, including fatigue and headaches, require greater attention during diagnosis in India.

Keywords:
DepressionFunctional somatic complaintsIndia

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Epidemiology

Background:

  • The Indian Psychiatric Society conducted a pilot multicentric study across diverse clinical settings.
  • This study aimed to understand the presentation of functional somatic complaints in a specific patient group.

Purpose of the Study:

  • To investigate the typology and prevalence of functional somatic complaints (FSCs) in patients experiencing their first episode of depression.
  • To explore the relationship between sociodemographic variables, depression severity, and FSCs.

Main Methods:

  • A total of 741 patients from 16 centers across India participated.
  • Assessments included the Bradford Somatic Symptom inventory for FSCs, Beck Depression Inventory for depression severity, and the Comprehensive Psychopathological Rating Scale- anxiety index (CPRS-AI).

Main Results:

  • The study sample had a mean age of 38.23 years with equal gender distribution.
  • A high prevalence of FSCs was observed, with 77% of patients reporting over 10 complaints, and 39.7% reporting over 20.
  • Common FSCs included lack of energy, headaches, fatigue, and various pains, influenced by sociodemographic factors and depression severity.

Conclusions:

  • Functional somatic symptoms are highly prevalent in Indian patients with depression.
  • These symptoms necessitate increased clinical attention during the diagnostic process for depression within the Indian context.