Related Experiment Video
Updated: May 13, 2026

An Open-Source Normothermic Perfusion System Designed for Research Scientists
Published on: July 18, 2025
International pediatric perfusion practice: 2011 survey results.
Brian Harvey1, Kenneth G Shann, David Fitzgerald
1Montefiore Medical Center, Bronx, New York, USA.
Pediatric congenital surgery centers show wide variation in cardiopulmonary bypass practices globally. Adoption of innovative techniques and devices differs significantly across geographic regions, indicating areas for improvement in pediatric cardiac surgery.
Area of Science:
- Pediatric Cardiac Surgery
- Cardiopulmonary Bypass Technology
- Surgical Innovation Adoption
Background:
- Numerous novel cardiopulmonary bypass (CPB) devices and innovative surgical methods are continually introduced.
- The extent of adoption of these advancements into routine clinical practice remains largely unquantified.
Purpose of the Study:
- To assess the current clinical practices and adoption rates of CPB technologies in pediatric congenital surgery centers worldwide.
- To identify variations in equipment and techniques across different geographic regions.
Main Methods:
- An electronic survey comprising 107 questions was distributed to 289 international pediatric congenital surgery centers.
- Responses from 146 (51%) centers were collected and analyzed, stratified by five distinct geographic regions.
Main Results:
- Most centers utilize hard shell venous reservoirs. Closed venous systems show higher adoption in Central/South America (50%) versus North America (3%) and Asia (10%).
- Modified ultrafiltration is employed by 71% of programs. Arterial bubble detection systems are universally used in North America and Oceana (100%) but less so in Central/South America (50%).
- Specific cardioplegia solutions exhibit regional preferences: "Del Nido" in North America (32%) and Custodial HTK in Europe (31%).
Conclusions:
- Significant geographic disparities exist in the adoption of CPB equipment and techniques within pediatric congenital surgery.
- These variations highlight opportunities for further research, standardization, and improvement in global pediatric cardiac surgical care.
More Related Videos
09:47Exploring Alternative Perfusion Solutions Using Next-Generation Polymerized Hemoglobin-Based Oxygen Carriers in a Model of Rat Ex Vivo Lung Perfusion
Published on: June 14, 2024
09:31Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
Published on: February 14, 2022