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Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
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Increased insulin sensitivity and distorted mitochondrial adaptations during muscle unloading.

Zhengtang Qi1, Yuan Zhang, Wei Guo

  • 1Key Laboratory of Adolescent Health Assessment and Exercise Intervention, Ministry of Education, East China Normal University, Shanghai 200241, China. szding@tyxx.ecnu.edu.cn.

International Journal of Molecular Sciences
|February 28, 2013
PubMed
Summary

Muscle disuse from hindlimb unloading (HU) improves insulin sensitivity and shifts fuel use to glucose. However, it also impairs mitochondrial biogenesis and dynamics, impacting muscle metabolism.

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