Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Publication time for letters. Letters are not published fast enough in the BMJ.

BMJ (Clinical research ed.)·1999
Same author

Driving simulation performance predicts future accidents among older drivers.

Journal of the American Geriatrics Society·1999
Same author

Traumatic rupture of the aortic arch treated by stent grafting.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·1999
Same author

Determinants responsible for assembly of the nicotinic acetylcholine receptor.

The Journal of general physiology·1999
Same author

Crystal structure of mouse acetylcholinesterase. A peripheral site-occluding loop in a tetrameric assembly.

The Journal of biological chemistry·1999
Same author

Nociceptive and antinociceptive responses to intrathecally administered nicotinic agonists.

Neuropharmacology·1999
Same journal

Pelvic venous disease and lymphatic dysfunction: evaluating the evidence for a proposed continuum.

The Journal of cardiovascular surgery·2026
Same journal

Incidence of post-dissection aneurysmal formation and need for secondary intervention after surgery for acute type A aortic dissections: a systematic review and meta-analysis of observational studies.

The Journal of cardiovascular surgery·2026
Same journal

The expertise effect: how advancing skills in frozen elephant trunk have broadened surgical indication for acute dissection.

The Journal of cardiovascular surgery·2026
Same journal

Outcomes of pulmonary embolism response teams: a systematic review.

The Journal of cardiovascular surgery·2026
Same journal

Use of large bore devices in the treatment of pulmonary embolism.

The Journal of cardiovascular surgery·2026
Same journal

Contemporary role of systemic thrombolysis in the management of acute pulmonary embolism.

The Journal of cardiovascular surgery·2026
See all related articles

Related Experiment Video

Updated: May 13, 2026

Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging
09:32

Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging

Published on: December 9, 2021

Future imaging techniques in aortic pathologies and clinical implications.

R Clough1, P Taylor

  • 1Department of Vascular Surgery and Imaging Sciences, NIHR Comprehensive Biomedical Research Centre of Guy's and St Thomas' NHS Foundation Trust and King's College London, King's Health Partners, St Thomas' Hospital, London, UK.

The Journal of Cardiovascular Surgery
|February 28, 2013
PubMed
Summary
This summary is machine-generated.

Future imaging techniques like molecular MRI and PET-CT offer advanced detection of aortic diseases. These methods identify at-risk patients for early intervention and personalized treatment, improving clinical outcomes.

More Related Videos

An Approach to Point-Of-Care Ultrasound Evaluation of the Abdominal Aorta
07:12

An Approach to Point-Of-Care Ultrasound Evaluation of the Abdominal Aorta

Published on: September 8, 2023

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

Related Experiment Videos

Last Updated: May 13, 2026

Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging
09:32

Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging

Published on: December 9, 2021

An Approach to Point-Of-Care Ultrasound Evaluation of the Abdominal Aorta
07:12

An Approach to Point-Of-Care Ultrasound Evaluation of the Abdominal Aorta

Published on: September 8, 2023

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Medical Diagnostics

Background:

  • Current computed tomography (CT) provides static images for aortic pathology, limiting early detection of subclinical changes.
  • Aortic diameter is a primary treatment indicator but can be prone to errors.
  • Novel imaging modalities are needed to assess aortic wall composition, function, and inflammation.

Purpose of the Study:

  • To explore advanced imaging techniques for early detection of subclinical aortic pathology.
  • To identify patients who would benefit from early surgical intervention or tailored medical treatment.
  • To enhance understanding of aortic disease pathophysiology for improved patient outcomes.

Main Methods:

  • Molecular magnetic resonance (MR) imaging to measure elastin in the aortic wall and assess endothelial permeability.
  • Blood pool contrast agent imaging for flow-independent assessment.
  • Four-dimensional phase contrast MR (4D PC-MR) imaging to quantify flow in aortic dissection lumens.
  • Hybrid positron emission tomography (PET) combined with CT (PET-CT) to evaluate aortic wall inflammation.

Main Results:

  • Molecular imaging can detect low elastin levels, identifying patients at risk for aortic dilatation.
  • MR techniques can identify endothelial dysfunction for personalized medical treatment.
  • 4D PC-MR quantifies flow, assesses false lumen expansion, and guides endovascular treatment for aortic dissection.
  • PET-CT indicates inflammation and predicts poor outcomes in dissection patients.

Conclusions:

  • Advanced imaging techniques combine anatomical and functional data for a comprehensive understanding of aortic pathology.
  • These novel methods enable earlier detection, risk stratification, and personalized management of aortic diseases.
  • Improved diagnostic capabilities are expected to lead to better clinical outcomes for patients with aortic conditions.