Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 13, 2026

Isolation and Purification of Murine Cardiac Pericytes
10:49

Isolation and Purification of Murine Cardiac Pericytes

Published on: August 16, 2019

Focus on cardiac pericytes.

Stephan Nees1, Dominik R Weiss, Gerd Juchem

  • 1Department of Physiology, University of Munich (LMU), Schillerstr. 44, 80336, Munich, Germany. stephan.nees@lrz.uni-muenchen.de

Pflugers Archiv : European Journal of Physiology
|February 28, 2013
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Case report: failed restoration of left ventricular function after myosplint® placement followed by successful HeartMate 3™ LVAD implantation.

European heart journal. Case reports·2026
Same author

Beyond Boundaries: Proposing an Extended Role for Rapid Deployment Valves in Aortic Valve Redo Surgery.

Interdisciplinary cardiovascular and thoracic surgery·2026
Same author

Transcranial doppler assessment of preoperative cerebral blood flow velocity in cardiac surgery patients.

Journal of clinical monitoring and computing·2025
Same author

Gender-Based Analysis of Patients Undergoing Mitral Valve Surgery.

Journal of clinical medicine·2025
Same author

Long-Term Continuous Monitoring of New-Onset Atrial Fibrillation After Coronary Artery Bypass Grafting.

JAMA·2025
Same author

Outcomes in Early Postoperative Versus Late New-Onset Atrial Fibrillation After Coronary Artery Bypass Grafting.

Journal of the American Heart Association·2025
Same journal

Expression of protein kinase A catalytic subunits in healthy and diseased mouse kidneys.

Pflugers Archiv : European journal of physiology·2026
Same journal

Localization of O₂‑sensing ADO‑RGS pathway components in mouse and human kidneys under normoxia, hypoxia and renal fibrosis.

Pflugers Archiv : European journal of physiology·2026
Same journal

Cholesterol-depleting dextrin depolarizes sarcolemma: the contribution of sodium / calcium channels and membrane integrity.

Pflugers Archiv : European journal of physiology·2026
Same journal

Inhibition of (interstitial) P2Y<sub>6</sub> receptors attenuates fibrosis progression.

Pflugers Archiv : European journal of physiology·2026
Same journal

Renal NHE3 is required to limit hypokalemia and metabolic acidosis during dietary potassium deficiency.

Pflugers Archiv : European journal of physiology·2026
Same journal

Xenin-25 improves indomethacin-induced acute gastric injury in rats.

Pflugers Archiv : European journal of physiology·2026
See all related articles

The heart

Area of Science:

  • Cardiovascular Biology
  • Vascular Physiology
  • Cardiac Pathogenesis

Background:

  • The myocardial microvasculature forms a critical barrier between blood and heart tissue.
  • Pericytes, embedded in the extracellular matrix, are integral components of this barrier.
  • This structure extends from capillaries to larger coronary vessels.

Purpose of the Study:

  • To elucidate the structural and functional roles of pericytes in myocardial vessels.
  • To explore the implications of pericyte function in cardiac disease.
  • To propose revised therapeutic strategies based on new pathogenetic models.

Main Methods:

  • Histological analysis of myocardial microvessels.
  • Investigation of pericyte localization and extracellular matrix interactions.

More Related Videos

Isolation of Perivascular Multipotent Precursor Cell Populations from Human Cardiac Tissue
08:15

Isolation of Perivascular Multipotent Precursor Cell Populations from Human Cardiac Tissue

Published on: October 8, 2016

Related Experiment Videos

Last Updated: May 13, 2026

Isolation and Purification of Murine Cardiac Pericytes
10:49

Isolation and Purification of Murine Cardiac Pericytes

Published on: August 16, 2019

Isolation of Perivascular Multipotent Precursor Cell Populations from Human Cardiac Tissue
08:15

Isolation of Perivascular Multipotent Precursor Cell Populations from Human Cardiac Tissue

Published on: October 8, 2016

  • Physiological assessment of solute transport across the vessel wall.

    • Main Results:

    • Myocardial terminal vessels possess a tight endothelial-pericyte barrier.
    • Pericytes are strategically located in both microvessels and the intima of larger coronary vessels.
    • These pericytes exhibit crucial histological and physiological functions.

    Conclusions:

    • Pericytes are key players in myocardial vascular function and integrity.
    • Understanding pericyte roles necessitates new models for heart disease pathogenesis.
    • Current therapeutic approaches for cardiac conditions may require revision.