Related Experiment Video
Updated: May 13, 2026

Determination of Reproductive Competence by Confirming Pubertal Onset and Performing a Fertility Assay in Mice and Rats
Published on: October 13, 2018
An unusual cause of delayed puberty: Berardinelli- Seip syndrome
Vimal Upreti1, Pawan Dhull, Saroj Kumar Patnaik
1Endocrinology, Command Hospital, Bangalore 560007, India. v_upreti123@rediffmail.com
Abstract:
Berardinelli- Seip syndrome is an autosomal recessive disorder characterized by generalized lipoatrophy, extreme insulin resistance with dyslipidemia in childhood and development of diabetes in adolescence. Menstrual irregularities are commonly seen as a result of secondary polycystic ovarian syndrome. Delayed puberty as a manifestation of these abnormalities in girls has rarely been described earlier. We report one such case patient who had delayed puberty and portal hypertension as unique features amongst the characteristic phenotypes of this syndrome.
Related Concept Videos
Signs of Puberty
Genomic Imprinting and Inheritance
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
Inborn Errors of Metabolism
Sex Linked Disorders
Psychosexual Stages of Personality: Latency
The latency period is not considered...
Meiosis I