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Related Experiment Video

Updated: May 13, 2026

Nerve-sparing Mid-urethral Obstruction (NeMO) in Female Small Rodents

Nerve-sparing Mid-urethral Obstruction (NeMO) in Female Small Rodents

Published on: April 25, 2017

Changes in sexual functioning in women after neuromodulation for voiding dysfunction.

Jessica M Yih¹, Kim A Killinger, Judith A Boura

¹Department of Urology, Beaumont Health System, Royal Oak, MI, USA.

The Journal of Sexual Medicine

|March 1, 2013

Summary

This summary is machine-generated.

Sacral neuromodulation improved sexual functioning in women with voiding issues, particularly those with lower baseline sexual function. The treatment positively impacted desire, orgasm, satisfaction, and pain, with some inactive women becoming active.

Keywords:

Electrical Stimulation Therapy Physiological Sexual Dysfunction Urination Disorders

Related Experiment Videos

Last Updated: May 13, 2026

Nerve-sparing Mid-urethral Obstruction (NeMO) in Female Small Rodents

Nerve-sparing Mid-urethral Obstruction (NeMO) in Female Small Rodents

Published on: April 25, 2017

Area of Science:

Urology
Neuroscience
Sexual Medicine

Background:

Sacral neuromodulation is an established treatment for urinary and bowel disorders.
Its potential application extends to sexual dysfunction.

Purpose of the Study:

To evaluate changes in female sexual functioning after sacral neuromodulation for voiding symptoms.
To assess the impact on different domains of sexual function and compare outcomes based on baseline sexual function.

Main Methods:

Prospective, observational study of 167 women undergoing sacral neuromodulation.
Collected data included Female Sexual Function Index (FSFI) and Interstitial Cystitis Symptom-Problem Indices (ICSI-PI) at baseline and follow-up.
Women were grouped by baseline FSFI scores (<26 and ≥26).

Main Results:

Overall FSFI scores improved significantly from pre-implant to 12 months post-implant (P=0.004).
Women with lower baseline sexual function (FSFI<26) showed significant improvements in desire, orgasm, satisfaction, and pain.
Ten women in the lower baseline group became sexually active, while the higher baseline group experienced a slight decline in overall scores.

Conclusions:

Sacral neuromodulation can lead to improvements in sexual functioning alongside urinary symptom relief.
Factors influencing sexual function are multifactorial, but neuromodulation shows promise for enhancing sexual health in this patient population.