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The evolving pattern of pediatric endocarditis from 1960 to 1985
F Coutlée1, A M Carceller, L Deschamps
1Department of Microbiology and Immunology, Université de Montréal, Québec.
The Canadian Journal of Cardiology
|May 1, 1990
Summary
Childhood endocarditis is rare but serious, with a high morbidity rate of 85.7%. This study highlights the poor prognosis and diagnostic delays in pediatric endocarditis cases.
Area of Science:
- Pediatric Cardiology
- Infectious Diseases
- Critical Care Medicine
Background:
- Endocarditis in children is uncommon but carries significant risks.
- Delayed diagnosis is a common issue, impacting patient outcomes.
Purpose of the Study:
- To analyze the clinical presentation, diagnosis, and outcomes of childhood endocarditis.
- To identify risk factors associated with increased mortality in pediatric endocarditis.
Main Methods:
- Retrospective analysis of 37 pediatric patients diagnosed with endocarditis.
- Diagnostic criteria included histology, blood cultures, echocardiography, and clinical syndrome.
- Etiologic agents and patient demographics were recorded.
Main Results:
- The mean delay to diagnosis was 35.8 days.
- Common symptoms included weakness and fever; streptococci and staphylococci were the most frequent pathogens.
- Mortality was 27%, with higher rates in infants, Aspergillus infections, and those without underlying heart disease.
Conclusions:
- Childhood endocarditis, though rare, has a poor prognosis and high morbidity (85.7%).
- Early diagnosis and prompt treatment are crucial for improving outcomes in pediatric endocarditis.
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