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Published on: December 31, 2015
Growth curves: how to best measure growth of the preterm infant
1Department of Pediatrics, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA 30912-3740, USA. jatindeb@georgiahealth.edu
Insights
Developing new growth curves for preterm infants is crucial. Current methods are ineffective, necessitating normative data from healthy premature neonates for accurate infant evaluation.
Area of Science:
- Neonatalogy
- Pediatric Growth and Development
- Anthropometry
Background:
- Birth weight is a key infant evaluation metric, typically compared against standard growth curves for full-term infants.
- Existing growth assessment methods for preterm infants are limited due to factors like unknown causes of premature birth and uncertain gestational age.
- Intrauterine growth curves, while used, are derived from cross-sectional data of premature infants and do not represent normal growth conditions.
Purpose of the Study:
- To address the limitations in evaluating preterm infants by establishing normative growth curves.
- To create growth references specifically for healthy preterm neonates.
- To provide a more accurate tool for assessing infant development post-birth.
Main Methods:
- The study highlights the need for developing new growth curves based on healthy preterm infants.
- It emphasizes the inadequacy of current cross-sectional intrauterine growth curves.
- The approach requires periodic updates to reflect contemporary health trends.
Main Results:
- Current standard growth curves are not well-suited for preterm infants.
- Intrauterine growth curves lack representation of normal growth.
- There is a clear need for normative growth data derived from healthy preterm populations.
Conclusions:
- Normative growth curves derived from healthy preterm infants are essential for accurate neonatal assessment.
- These new curves will improve the evaluation of infants born prematurely.
- Regular updates are recommended to maintain relevance with changing population health and maternal characteristics.
Abstract:
Birth weight is one of the most important anthropometric measures in the evaluation of an infant. For the full-term infant, birth weight is compared with reference or standard growth curves that are constructed by plotting weight, length, and head circumference against postnatal age. Following a similar approach for preterm infants is less effective for a variety of reasons. Birth weight and other anthropometric measures used to evaluate an infant at birth are influenced by various maternal characteristics, the intrauterine milieu, and duration of gestation. Second, the causes of premature birth and their impact on birth weight are largely unknown. Third, gestational age is difficult to determine with full certainty. One approach that has been used to circumvent these issues is to use intrauterine growth reference curves. However, these curves do not really reflect "normal" growth because they were constructed using cross-sectional data from infants born prematurely and, as such, do not reflect the normal condition. Thus, there is a need to develop normative growth curves derived from "healthy" preterm infants that can be applied to neonates born prematurely. These should be updated periodically to reflect secular trends in maternal body weight, height, and overall health.
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