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Updated: May 13, 2026

Transcutaneous Microcirculatory Imaging in Preterm Neonates
Published on: December 31, 2015
Selected macro/micronutrient needs of the routine preterm infant
Jatinder Bhatia1, Ian Griffin, Diane Anderson
1Medical College of Georgia, Georgia Health Sciences University, Augusta, GA 30912, USA. jatindeb@georgiahealth.edu
Optimal nutrition for premature infants is not well-defined. This review defines optimal intakes for key micronutrients like calcium, phosphorus, magnesium, vitamin D, iron, and copper to improve infant outcomes and prevent disorders.
Area of Science:
- Neonatal nutrition
- Pediatric micronutrient requirements
Background:
- Optimal nutrition for premature infants, particularly micronutrients, remains undefined.
- The "reference fetus" model aids in determining nutritional needs for preterm infants.
- Establishing precise nutrient requirements can enhance infant outcomes and prevent conditions like metabolic bone disease and anemia.
Purpose of the Study:
- To review and define optimal intake levels for key micronutrients in premature infants.
- To provide evidence-based recommendations for calcium, phosphorus, magnesium, vitamin D, iron, and copper.
Main Methods:
- Literature review of published data on micronutrient requirements in preterm infants.
- Analysis of the "reference fetus" model for nutritional needs assessment.
Main Results:
- Defined optimal intake ranges for calcium, phosphorus, magnesium, vitamin D, iron, and copper.
- Highlighted the importance of these micronutrients for preterm infant growth and development.
Conclusions:
- Revised nutrient requirements and optimal provision are crucial for improving preterm infant health.
- Adequate micronutrient intake helps prevent common nutritional deficiencies and associated disorders in premature neonates.
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