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Related Concept Videos

Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
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Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase

Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...
Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu01:29

Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu

Genetic variations significantly influence drug response through pharmacokinetics, receptor interactions, and biologic milieu modifications. Pharmacokinetic alterations impact drug metabolism and clearance, affecting efficacy and toxicity. Variants in drug-metabolizing enzymes, such as CYP2C9 and CYP2C19, alter drug activation and elimination. For example, CYP2C9 loss-of-function variants require lower warfarin doses to prevent excessive bleeding, while CYP2C19 variants reduce clopidogrel...
Pharmacogenetics and Pharmacogenomics: Overview01:29

Pharmacogenetics and Pharmacogenomics: Overview

Pharmacogenetics and pharmacogenomics examine how genetic factors influence an individual's response to drugs. While pharmacogenetics focuses on the impact of specific genetic variants on drug effects, pharmacogenomics takes a broader approach, studying how genetic variation across populations contributes to differences in drug responses. These fields aim to explain why individuals may experience varying levels of efficacy or adverse reactions to the same medication.Variability in drug...
Introduction to Biological Bases of Psychology01:30

Introduction to Biological Bases of Psychology

Biopsychology serves as a vital bridge connecting the intricate domains of biology and psychology, shedding light on how biological systems influence psychological phenomena. This field scrutinizes the biological substrates of behavior and mental processes, emphasizing the nervous system along with the roles of neurotransmitters, hormones, and genetics. It also incorporates evolutionary perspectives to explain the adaptive nature of mental functions.
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Related Experiment Video

Updated: May 13, 2026

Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting
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Published on: November 30, 2015

[Pyschotherapygenetics. Do genes influence psychotherapy adherence?].

Víctor Pérez1, Juan Carlos Pascual, Joaquim Soler

  • 1Departamento de Psiquiatría, Hospital de la Santa Creu i Sant Pau, Barcelona, España; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Universidad Autónoma de Barcelona, Barcelona, España.

Revista De Psiquiatria Y Salud Mental
|March 1, 2013
PubMed
Summary
This summary is machine-generated.

Certain serotonin transporter gene variations are linked to better adherence in dialectical behavioral therapy (DBT) for borderline personality disorder (BPD) patients. This suggests a role for "psychotherapygenetics" in understanding treatment response.

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Area of Science:

  • Psychiatric genetics
  • Behavioral science

Context:

  • Borderline personality disorder (BPD) presents challenges in treatment adherence.
  • Dialectical behavioral therapy (DBT) is a common treatment for BPD.
  • Genetic factors may influence patient engagement in psychotherapy.

Purpose:

  • To investigate the association between specific gene polymorphisms (SERT and DRD4) and adherence to DBT in BPD patients.
  • To explore the concept of
  • psychotherapygenetics
  • as a framework for understanding genetic influences on therapeutic outcomes.

Summary:

  • A prospective study examined 110 BPD patients undergoing DBT.
  • Polymorphisms in the serotonin transporter gene (SERT) and dopamine 4-receptor gene (DRD4) were analyzed.
  • Higher adherence to DBT was associated with the 12-repeat allele of the SERT VNTR polymorphism.

Impact:

  • Preliminary findings suggest a correlation between specific genetic variations and psychotherapy adherence in BPD.
  • The
  • psychotherapygenetics
  • approach may offer insights into how genetic factors influence patient response to therapy.