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Does the z-score value of the abdominal aorta predict recoarctation in an infant?
Canan Ayabakan1, Köksal Binnetoğlu, Özlem Sarisoy
1Başkent University İstanbul Research Hospital, İstanbul, Turkey. cayabakan@yahoo.com
Insights
Balloon angioplasty for coarctation of the aorta is controversial due to restenosis. An abdominal aorta z-score of 0.42 can help identify infants at lower risk of recoarctation after this procedure.
Area of Science:
- Pediatric Cardiology
- Cardiovascular Surgery
- Medical Imaging
Background:
- Coarctation of the aorta (CoA) is a congenital heart defect requiring intervention.
- Balloon angioplasty (BAP) and surgical repair are primary treatment options for CoA.
- Restenosis, or recoarctation, remains a significant concern after intervention.
Purpose of the Study:
- To evaluate left ventricular dimensions and aortic arch z-scores in infants with CoA.
- To identify risk factors predicting recoarctation after BAP or surgery for CoA.
Main Methods:
- Retrospective evaluation of 44 infants (2 days-24 months) with CoA between 2007-2011.
- Measurement of left ventricular dimensions, systolic functions, and various aortic segments with z-score determination.
- Analysis of recoarctation rates and associated risk factors, including abdominal aorta z-scores.
Main Results:
- 14 out of 33 (42%) infants who underwent successful primary BAP experienced recoarctation.
- Infants in the recoarctation group had significantly lower abdominal and transverse aorta z-scores.
- An abdominal aorta z-score of 0.42 demonstrated 88.9% sensitivity and 53.8% specificity for predicting recoarctation.
Conclusions:
- Despite high restenosis rates, BAP is a viable option for native coarctation.
- An abdominal aorta z-score cutoff of 0.42 can aid in selecting patients for primary BAP.
- Utilizing this z-score may help reduce the incidence of recoarctation following BAP for CoA.
Objective:
We evaluated left ventricular dimensions and aortic arch z-scores in infants who underwent balloon angioplasty (BAP) or surgery for coarctation of aorta (CoA). We searched for risk factors predicting recoarctation.
Patients:
Between 2007-2011, 27 male and 17 female infants (mean age 2.93 ± 4.78 months, range 2 days-24 months) with CoA were evaluated. Left ventricular dimensions, systolic functions, mitral and aortic annuli, transverse aortic arch, isthmus, coarctation site, and diaphragmatic aorta measurements were done and z-scores were determined before intervention.
Results:
Six patients underwent primary operation, 38 patients had BAP (86.4%). Associated cardiac pathologies in operated patients were double outlet right ventricle (n = 2), atrioventricular septal defect (n = 1), Ebstein's anomaly (n = 1), arch hypoplasia (n = 2). Twelve patients (27.2%) had simple coarctation. Ventricular septal defect was the most frequent associated cardiac pathology (n = 20, 45.4%). The patients were followed for 10.22 ± 8.21 months. Among 33 primary successful BAP's, 14 had recoarctation (42%). Eleven patients were primarily operated (including 5 with unsuccessful BAP), two had recoarctation (18%). Abdominal and transverse aorta values and z-scores were significantly lower in the recoarctation group (7.15 ± 2.12 mm and 6.07 ± 1.86 mm respectively in the "no-recoarctation group"; vs. 5.53 ± 0.75 mm and 4.94 ± 1.53 mm in the "recoarctation group" P <.05). Abdominal aorta z-score of 0.42 was 88.9% sensitive and 53.8% specific to predict recoarctation (area under ROC curve: 0.618-0.902, P <.05).
Conclusion:
Although BAP for native coarctation is still a controversial treatment option due to frequent restenosis rates, abdominal aorta z-score of 0.42 could correctly eliminate recoarctation in 89% of these cases. This cutoff value might help us choose patients for primary BAP and decrease the recoarctation rate after BAP.
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