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Updated: May 13, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation
Published on: January 17, 2011
Incidence of post-intubation subglottic stenosis in children: prospective study
C Schweiger1, P J Cauduro Marostica, M M Smith
1Department of Otolaryngology, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil. causch@hotmail.com
Insights
The incidence of subglottic stenosis in children after endotracheal intubation is high. Further research is needed to identify risk factors for this condition.
Area of Science:
- Pediatric critical care medicine
- Otolaryngology
- Respiratory medicine
Background:
- Endotracheal intubation is a common procedure in pediatric intensive care units.
- Subglottic stenosis is a potential complication of prolonged intubation in children.
- Early identification and management are crucial for favorable outcomes.
Purpose of the Study:
- To determine the incidence of subglottic stenosis in pediatric patients following endotracheal intubation.
- To assess the relationship between laryngeal alterations post-extubation and the development of subglottic stenosis.
Main Methods:
- A prospective study was conducted on 123 children in a tertiary care hospital's pediatric intensive care unit.
- Flexible fiber-optic nasolaryngoscopy was performed after extubation and during follow-up.
- Children were categorized based on laryngeal findings to assess the development of subglottic stenosis.
Main Results:
- The overall incidence of subglottic stenosis was 11.38% (95% CI, 6.63-17.94%).
- All children diagnosed with subglottic stenosis exhibited moderate to severe laryngeal alterations immediately after extubation.
- No chronic changes were observed in children with normal initial post-extubation laryngeal examinations.
Conclusions:
- The incidence of subglottic stenosis in this cohort is notably high.
- Moderate to severe laryngeal alterations post-extubation are indicative of increased risk.
- Further investigation into specific risk factors is warranted to guide preventative strategies.
Objective:
To evaluate the incidence of subglottic stenosis in children undergoing endotracheal intubation.
Methods:
Children in the paediatric intensive care unit of a tertiary care hospital were considered eligible for inclusion if they received endotracheal intubation for more than 24 hours. After extubation, children underwent flexible fibre-optic nasolaryngoscopy. Based on this first evaluation, they were divided into two groups: 'acute normal', with mild laryngeal alterations or normal findings; and 'acute alterations', with moderate to severe laryngeal alterations. Further laryngoscopic follow up (7-10 days later) was undertaken for those children in the acute normal group who developed symptoms during follow up (after discharge from the intensive care unit), and for all children in the acute alterations group. Children were then classified into two final groups: 'normal final examination', with no chronic changes; and 'subglottic stenosis'.
Results:
We included 123 children. The incidence of subglottic stenosis was 11.38 per cent (95 per cent confidence interval, 6.63-17.94 per cent). All the children who developed subglottic stenosis had had moderate to severe alterations immediately after extubation.
Conclusion:
This incidence of subglottic stenosis is quite high and needs further investigation to identify risk factors.
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