Related Experiment Video
Updated: May 13, 2026
09:01
The Bovine Lung in Biomedical Research: Visually Guided Bronchoscopy, Intrabronchial Inoculation and In Vivo Sampling Techniques
Published on: July 3, 2014
Pulmonary involvement in brucellosis.
1Department of Infectious Diseases and Clinic Microbiology;
Summary
Brucellosis, a zoonotic disease, can rarely affect the lungs. This case highlights pulmonary brucellosis in a woman treated successfully with doxycycline and rifampicin, emphasizing its consideration in endemic areas.
Area of Science:
- Infectious Diseases
- Pulmonology
- Zoonotic Diseases
Background:
- Brucellosis is a multisystem zoonotic disease caused by Brucella genus bacteria.
- It primarily affects the reticuloendothelial system, joints, heart, and kidneys.
- Pulmonary involvement in brucellosis is considered rare, despite potential inhalation transmission.
Observation:
- A previously healthy 36-year-old woman presented with fever, cough, and chest pain, initially diagnosed as pneumonia.
- She showed no improvement with standard antibiotic treatment for pneumonia.
- Diagnostic tests revealed high titres for Brucella (Wright and Coombs tests), and chest radiography indicated lobar consolidation.
Findings:
- The patient was successfully treated with a six-week course of doxycycline and rifampicin.
- Rapid clinical improvement was observed following the initiation of this specific antibiotic regimen.
- One-year follow-up confirmed no residual effects from the brucellosis infection.
Implications:
- This case underscores that pulmonary brucellosis, while uncommon, can mimic other respiratory illnesses.
- In regions where brucellosis is endemic, it should be considered in the differential diagnosis of patients with persistent pulmonary symptoms.
- Increased awareness and diagnostic consideration can lead to timely and effective treatment of pulmonary brucellosis.
Related Concept Videos
01:31Pulmonary Tuberculosis III
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
01:28Pulmonary Tuberculosis II
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
01:29Pulmonary Tuberculosis I
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
01:24Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
01:26Pulmonary Tuberculosis IV
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
01:17Other Pulmonary Disorders
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.