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Updated: May 13, 2026

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
10:26

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

Medical management of venous thromboembolism: what the interventional radiologist needs to know

Raj S Kasthuri1, Nigel S Key

  • 1Division of Hematology/Oncology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Seminars in Interventional Radiology
|March 2, 2013
PubMed

Insights

Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, affects 1-3 per 1000 people. This review discusses VTE risk factors, anticoagulation duration, and emerging oral anticoagulant treatments.

Area of Science:

  • Cardiovascular Medicine
  • Hematology

Background:

  • Deep vein thrombosis and pulmonary embolism are manifestations of venous thromboembolism (VTE).
  • VTE affects 1-3 per 1000 individuals, with incidence projected to rise due to increased life expectancy.
  • Current VTE treatment relies on anticoagulation, with duration dependent on the thrombotic event's context.

Purpose of the Study:

  • To review risk factors associated with VTE.
  • To outline the approach for determining anticoagulation duration in VTE patients.
  • To discuss clinical trial results of new oral anticoagulants for VTE treatment.

Main Methods:

  • Review of existing literature on VTE.
  • Analysis of clinical trial data for novel oral anticoagulants.
  • Discussion of risk stratification and anticoagulation management strategies.

Main Results:

  • Vitamin K antagonists, the current oral standard, have drawbacks.
  • New oral anticoagulants are in development and show promise for VTE treatment.
  • Determining anticoagulation duration requires careful consideration of individual patient factors.

Conclusions:

  • VTE remains a significant health concern with increasing incidence.
  • Optimizing anticoagulation duration is crucial for effective VTE management.
  • Novel oral anticoagulants may offer improved VTE treatment options.

Keywords:
anticoagulationmedical managementthrombophilia testingvenous thromboembolism

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