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Updated: May 13, 2026
Assessment of the Metabolic Profile of Primary Leukemia Cells
Published on: November 21, 2018
Transient leukaemia: leukaemia or leukaemoid? A diagnostic dilemma
Nisha Marwah1, Shilpi Modi, Veena Gupta
1Department of Pathology, Pt. B.D. Sharma PGIMS, 2452, Sector-1, HUDA, Rohtak, 124001 India.
Abstract:
We report a case of a newborn male who had mongoloid slant and was hypotonic at birth. Routine investigations revealed leucocytosis (WBC > 70,000/cmm) with 50% blasts in peripheral blood film. Marrow examination confirmed the excess of blasts. Karyotyping revealed 47, XY + 21 chromosomes. Due to absence of clinical symptoms, the baby was kept on follow-up without treatment. Within 7 weeks, PBF and bone marrow findings returned to normal, and the child was diagnosed as having Transient leukaemia with Down syndrome.
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