Related Experiment Video
Updated: May 13, 2026

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
Published on: November 18, 2018
Unroofed coronary sinus and persistent left superior vena cava: A case report
M Bonardi1, A Valentini, R Camporotondo
1IRCCS Foundation, San Matteo Medical Center, Radiology, Pavia, Italy.
Insights
A rare heart defect called an unroofed coronary sinus, often linked with persistent left superior vena cava, can be hard to diagnose. This case highlights its discovery via CT scan during pulmonary hypertension evaluation.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Unroofed coronary sinus is a spectrum of cardiac anomalies characterized by partial or complete absence of the interatrial wall separating the coronary sinus from the left atrium.
- These anomalies frequently coexist with anomalous systemic venous return, notably persistent left superior vena cava.
- Diagnosis can be challenging due to nonspecific clinical presentations, impacting patient prognosis.
Purpose of the Study:
- To report a case of a complete unroofed coronary sinus and persistent left superior vena cava.
- To illustrate the utility of computed tomography in diagnosing this rare cardiac anomaly in the context of pulmonary hypertension.
Main Methods:
- Computed tomography (CT) investigation was performed.
- The diagnostic process involved detailed imaging analysis to identify cardiac anomalies.
Main Results:
- A complete unroofed coronary sinus was identified.
- A persistent left superior vena cava was also diagnosed.
- These findings were discovered during a CT scan for pulmonary hypertension.
Conclusions:
- The case demonstrates the successful diagnosis of a complete unroofed coronary sinus and persistent left superior vena cava using computed tomography.
- This highlights the importance of advanced imaging in diagnosing rare cardiac anomalies, especially when presenting with conditions like pulmonary hypertension.
Abstract:
The unroofed coronary sinus is a spectrum of cardiac anomalies in which part or all of the common wall between the coronary sinus and the left atrium is absent. Most cases are associated with anomalous systemic venous return, such as persistent left superior vena cava.The diagnosis of this lesion is important to the prognosis of the patient, but it is often difficult because of nonspecific clinical features.Here we report a case of a complete unroofed coronary sinus and persistent left superior vena cava discovered during a computed tomographic investigation for pulmonary hypertension.
More Related Videos
Related Concept Videos
Overview of Systemic Veins
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the middle...
Coronary Circulation
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Mitral Regurgitation I: Introduction
Mitral Stenosis I: Introduction

