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Published on: February 9, 2021
Association between prostate cancer and urinary calculi: a population-based study.
Shiu-Dong Chung1, Shih-Ping Liu, Herng-Ching Lin
1Division of Urology, Department of Surgery, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
Plos One
|March 2, 2013
Summary
Individuals with a history of urinary calculi (UC) have a significantly higher risk of developing prostate cancer (PC). This finding suggests UC may be a risk factor for PC, potentially aiding in early detection strategies.
Area of Science:
- Urology
- Oncology
- Epidemiology
Background:
- Prostate cancer (PC) demographics are changing in Asia.
- The potential link between urinary calculi (UC) and PC requires investigation.
Purpose of the Study:
- To explore the association between a prior diagnosis of urinary calculi (UC) and prostate cancer (PC).
Main Methods:
- A population-based case-control study was conducted in Taiwan.
- 2,900 PC patients (cases) and 14,500 controls without PC were analyzed.
- Conditional logistic regression models were used to assess the association.
Main Results:
- A significant association was found between prior UC and PC (OR=1.63).
- Cases were more likely to have prior kidney, bladder, or unspecified calculi.
- No significant association was observed with ureter calculus.
Conclusions:
- Prior urinary calculi are associated with an increased risk of prostate cancer.
- This association may inform targeted screening for PC in individuals with a history of UC.
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