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Related Concept Videos

Increased Body Temperature01:25

Increased Body Temperature

A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
Homeostatic Imbalances in Body Temperature01:19

Homeostatic Imbalances in Body Temperature

Hyperthermia occurs when the body's temperature becomes unusually high, often due to heat exposure, intense physical activity, or certain illnesses. This condition can create a dangerous cycle where elevated body temperature increases the metabolic rate, generating more heat and potentially leading to organ failure and brain damage. A severe form of hyperthermia, called heat stroke, can raise body temperature to life-threatening levels. Fever, on the other hand, is a controlled form of...
Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Decreased Body Temperature01:29

Decreased Body Temperature

A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...
Masonry in Cold and Hot Weather Conditions01:21

Masonry in Cold and Hot Weather Conditions

In cold weather, masonry construction requires specific precautions to ensure mortar does not freeze before curing, as this can significantly weaken its strength and watertightness. Mortar temperature should be maintained between 60°F and 80°F to support proper hydration and curing. Below 40°F, mortar water must be heated, but should not exceed 120°F as high temperatures can reduce mortar's compressive and bond strength.
Other key practices include keeping masonry units and sand dry and...
Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...

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Related Experiment Video

Updated: May 13, 2026

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model
13:41

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Published on: January 13, 2023

Developing effective drills in preparation for a malignant hyperthermia crisis.

Sharon J Hirshey Dirksen1, Sharon A Van Wicklin, Darlene Ledrut Mashman

  • 1Malignant Hyperthermia Association of the United States (MHAUS), Sherburne, NY, USA.

AORN Journal
|March 5, 2013
PubMed
Summary

A malignant hyperthermia (MH) crisis requires a rapid, coordinated team response for patient survival. Regular education and practice through MH mock drills are essential for effective management.

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Last Updated: May 13, 2026

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model
13:41

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

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Protocol for Long Duration Whole Body Hyperthermia in Mice
07:56

Protocol for Long Duration Whole Body Hyperthermia in Mice

Published on: August 25, 2012

A Preclinical Model of Exertional Heat Stroke in Mice
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A Preclinical Model of Exertional Heat Stroke in Mice

Published on: July 1, 2021

Area of Science:

  • Anesthesiology
  • Critical Care Medicine
  • Pharmacology

Background:

  • Malignant hyperthermia (MH) is a rare but life-threatening pharmacogenetic disorder of skeletal muscle.
  • MH crises are medical emergencies necessitating immediate and coordinated intervention.
  • Infrequent occurrence necessitates continuous education and preparedness.

Purpose of the Study:

  • To emphasize the critical need for a swift, multidisciplinary team response during malignant hyperthermia crises.
  • To highlight the importance of regular education and simulation for healthcare professionals.
  • To advocate for the development and practice of an organizational MH response plan.

Main Methods:

  • Review of diagnosis, treatment, and management protocols for malignant hyperthermia.
  • Development of a tailored MH response plan for healthcare organizations.
  • Implementation of periodic education sessions and simulation exercises (mock drills).

Main Results:

  • A coordinated, multidisciplinary team approach is vital for successful MH crisis outcomes.
  • Periodic review and reinforcement of MH management details are crucial.
  • Practicing MH response plans through simulations enhances team readiness.

Conclusions:

  • Effective management of malignant hyperthermia crises hinges on preparedness and rapid response.
  • Organizational MH response plans, regularly practiced, are key to mitigating MH emergencies.
  • Continuous education and simulation are indispensable for healthcare teams managing MH.