Related Experiment Video
Updated: May 13, 2026

06:29
Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
Giant left atrium associated with massive thrombus formation
Ahmad K Darwazah1, Hamdy El Sayed
1Heliopolis Cardiac Center, 46 Nazeeh Khalefa St, Heliopolis, Cairo, Egypt. darwaz30@hotmail.com.
Thrombosis Journal
|March 5, 2013
Summary
Giant left atrium, a severe heart enlargement, was successfully treated in a 45-year-old female. The condition, linked to rheumatic mitral valve disease, involved a large thrombus requiring surgical removal and valve replacement.
Area of Science:
- Cardiology
- Cardiac Surgery
Background:
- Giant left atrium (GLA) is defined by significant left atrial enlargement (diameter >65mm).
- Rheumatic heart disease, particularly mitral valve disease, is the most common etiology of GLA.
Observation:
- A 45-year-old female presented with symptoms attributed to rheumatic mitral stenosis.
- Imaging revealed a giant left atrium measuring 11 × 10 × 5 cm, containing a substantial 500g thrombus.
Findings:
- The patient underwent successful mitral valve replacement surgery.
- A large left atrial thrombus was completely removed (thrombectomy) using an inverted T-shaped biatrial incision.
Implications:
- This case highlights the successful surgical management of a rare giant left atrium with a massive thrombus.
- The inverted T-shaped biatrial incision facilitated complete thrombectomy and valve replacement, offering a viable surgical approach.
Related Concept Videos
Coronary Circulation
The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Mitral Stenosis I: Introduction
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Chambers of the Heart
The human heart is a complex organ made up of four chambers: the right and left atria and the right and left ventricles. These internal chambers are separated by partitions known as the interatrial and interventricular septa. The exterior of the heart features a groove known as the coronary sulcus that demarcates the atria from the ventricles, while the anterior and posterior interventricular sulci distinguish between the two ventricles.
Deoxygenated blood from the body is received in the right...
Deoxygenated blood from the body is received in the right...
Overview of Systemic Veins
Systemic veins are crucial blood vessels that return deoxygenated blood from various body tissues back to the heart. There are three systemic veins that return deoxygenated blood to the heart, they are as follows.
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the middle...
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the middle...
Venous Thrombosis I: Introduction
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
Aortic Regurgitation I: Introduction
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...

