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[Pediatric seizures and end-stage renal disease]

B Roland-Gosselin1, B Ranchin, A-L Leclerc

  • 1Service de néphrologie rhumatologie dermatologie pédiatriques, centre de référence des maladies rénales rares néphrogones, hôpital Femme-Mère-Enfant, 69677 Bron, France.

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|March 5, 2013
PubMed

Insights

Hypocalcemic seizures can occur in adolescents with undiagnosed end-stage renal disease. Early screening of calcium, phosphate, and creatinine is vital for children with growth issues or seizures.

Area of Science:

  • Pediatric Nephrology
  • Pediatric Neurology
  • Endocrinology

Background:

  • Hypocalcemia commonly presents with seizures in neonates and infants.
  • Seizures are less frequent in older children and adolescents with hypocalcemia.
  • Undiagnosed end-stage renal disease can lead to metabolic disturbances and skeletal issues.

Observation:

  • A 16-year-old girl experienced hypocalcemic seizures.
  • The patient had undiagnosed end-stage renal disease (ESRD).
  • She also presented with progressive growth retardation and bone deformities.

Findings:

  • This case highlights hypocalcemic seizures as a manifestation of ESRD in an adolescent.
  • Serum calcium, phosphate, and creatinine levels are crucial diagnostic markers.
  • Pediatric renal osteodystrophy can present with diverse clinical features.

Implications:

  • Early detection of hypocalcemia in children with seizures or bone abnormalities is critical.
  • Screening for renal function is essential in pediatric patients with unexplained growth retardation.
  • Prompt diagnosis and management of renal osteodystrophy can prevent severe complications.

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