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Updated: May 13, 2026

A Simple Fluorescence-based Reporter Assay to Identify Cellular Components Required for Ricin Toxin A Chain (RTA) Trafficking in Yeast
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A Simple Fluorescence-based Reporter Assay to Identify Cellular Components Required for Ricin Toxin A Chain (RTA) Trafficking in Yeast

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Targeting ricin to the ribosome

Kerrie L May1, Qing Yan, Nilgun E Tumer

  • 1Department of Plant Biology and Pathology, School of Environmental and Biological Sciences, Rutgers University, 59 Dudley Road, New Brunswick, NJ 08901-8520, USA.

Toxicon : Official Journal of the International Society on Toxinology
|March 5, 2013
PubMed
Summary

Ricin toxin disables protein synthesis by damaging ribosomes. Understanding toxin-ribosome interactions, particularly the ribosomal stalk, is key to developing antidotes for ricin and related ribosome inactivating proteins (RIPs).

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