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Updated: May 13, 2026

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Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
Quantitative transverse flow measurement using optical coherence tomography speckle decorrelation analysis
Xuan Liu1, Yong Huang, Jessica C Ramella-Roman
1Department of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, Maryland 21218, USA. xliu35@jhu.edu
Optics Letters
|March 5, 2013
Abstract:
We propose an inter-Ascan speckle decorrelation based method that can quantitatively assess blood flow normal to the direction of the optical coherence tomography imaging beam. To validate this method, we performed a systematic study using both phantom and in vivo animal models. Results show that our speckle analysis method can accurately extract transverse flow speed with high spatial and temporal resolution.
