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Related Experiment Video

Updated: May 13, 2026

Murine Bilateral Renal Lymphadenectomy
06:31

Murine Bilateral Renal Lymphadenectomy

Published on: December 30, 2025

Bilateral Wilms' tumour in a developing country: a descriptive study.

G P Hadley1, M Mars, P K Ramdial

  • 1Department of Paediatric Surgery, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa. hadley@ukzn.ac.za

Pediatric Surgery International
|March 5, 2013
PubMed
Summary

Bilateral Wilms' tumour is treatable even in resource-limited settings. This study highlights successful outcomes in children with this rare cancer, emphasizing the importance of tailored treatment strategies.

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Area of Science:

  • Pediatric Oncology
  • Nephrology
  • Surgical Oncology

Background:

  • Bilateral Wilms' tumour is a rare pediatric malignancy.
  • Management in resource-constrained environments presents unique challenges.
  • Understanding outcomes in diverse settings is crucial for global health equity.

Purpose of the Study:

  • To report the experience of managing 20 children with bilateral Wilms' tumour.
  • To analyze treatment outcomes in a resource-challenged setting over a decade.
  • To assess the feasibility of treating this rare condition under limitations.

Main Methods:

  • Retrospective review of patients diagnosed with bilateral synchronous Wilms' tumour.
  • Analysis of clinical presentation, treatment modalities, and survival data.

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Last Updated: May 13, 2026

Murine Bilateral Renal Lymphadenectomy
06:31

Murine Bilateral Renal Lymphadenectomy

Published on: December 30, 2025

  • Evaluation of surgical approaches and histopathological findings.

    • Main Results:

    • Bilateral Wilms' tumour represented 11% of all Wilms' tumour cases.
    • 20% of patients presented with metastatic disease; others had specific complications.
    • Nephron-sparing surgery was performed in 22 kidneys; 2-year overall survival was 85%.

    Conclusions:

    • Bilateral Wilms' tumour can be effectively treated despite significant comorbidities and advanced disease.
    • Resource-constrained environments can achieve favorable outcomes with appropriate management.
    • This study underscores the treatability of Wilms' tumour globally.