Related Experiment Video

Updated: May 13, 2026

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
06:59

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation

Published on: February 29, 2020

Recurrent bacterial meningitis in a child with hearing impairment, mondini dysplasia: a case report

Behdad Gharib1, Sara Esmaeili, Golnaz Shariati

  • 1Department of Pediatrics, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

Acta Medica Iranica
|March 5, 2013
PubMed

Insights

Recurrent bacterial meningitis in a boy was linked to inner ear malformation. Computed tomography scans revealed Mondini dysplasia, a potential predisposing factor for recurrent infections.

Area of Science:

  • Neuroscience
  • Otolaryngology
  • Infectious Diseases

Background:

  • Recurrent bacterial meningitis is uncommon, prompting investigation into predisposing factors.
  • Potential causes include anatomical abnormalities and immunodeficiency.
  • Identifying underlying conditions is crucial for managing recurrent meningitis.

Observation:

  • A case study of a young male patient with recurrent bacterial meningitis.
  • The patient had a history of head trauma and sensorineural hearing loss.
  • Clinical presentation suggested an underlying anatomical issue.

Findings:

  • Computed tomography (CT) scans of the temporal bones were performed.
  • The scans revealed Mondini dysplasia, an inner ear malformation.
  • This anatomical anomaly is a potential predisposing factor for recurrent meningitis.

Implications:

  • Mondini dysplasia should be considered in patients with recurrent meningitis, especially with hearing loss.
  • Early diagnosis of inner ear malformations can guide management strategies.
  • Further research may elucidate the link between specific anatomical defects and meningitis risk.

More Related Videos

Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages09:09

Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages

Published on: April 11, 2025

Neonatal Murine Cochlear Explant Technique as an In Vitro Screening Tool in Hearing Research08:30

Neonatal Murine Cochlear Explant Technique as an In Vitro Screening Tool in Hearing Research

Published on: June 8, 2017

Related Concept Videos

Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
Hearing01:31

Hearing

When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.