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Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
Conduction disorders in the setting of transcatheter aortic valve implantation: a clinical perspective
Chiara Fraccaro1, Massimo Napodano, Giuseppe Tarantini
1Division of Cardiology, Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Padova, Italy. chiara_fraccaro@hotmail.com
Insights
Transcatheter aortic valve implantation (TAVI) can cause conduction disorders (CDs) and require permanent pacemakers (PPMs). Pre-existing CDs and CoreValve use predict PPM need after TAVI.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Electrophysiology
Background:
- Conduction disorders (CDs) and permanent pacemaker (PPM) implantation are common after transcatheter aortic valve implantation (TAVI).
- Limited data exists on the prognostic and therapeutic impact of these post-TAVI complications.
- CD occurrence post-TAVI is linked to procedural conduction system trauma.
Purpose of the Study:
- To analyze current data on conduction disorders and PPM implantation following TAVI.
- To identify predictors for PPM implantation after TAVI.
- To propose clinical strategies for preventing and managing these complications.
Main Methods:
- Review and analysis of existing literature on TAVI-related conduction disorders and PPM implantation.
- Identification of key procedural and patient-related factors associated with PPM need.
- Synthesis of clinical data to formulate practical management guidelines.
Main Results:
- Predictors for PPM implantation post-TAVI include the use of CoreValve prosthesis and pre-existing CDs.
- Procedural trauma is a likely cause of new-onset CDs after TAVI.
- Effective pre-TAVI screening, precise valve deployment, and diligent post-TAVI monitoring are crucial.
Conclusions:
- Careful patient selection and procedural execution can minimize the need for PPM after TAVI.
- Understanding predictors aids in risk stratification and management planning.
- Further research is needed to fully elucidate the long-term implications of TAVI-induced CDs.
Abstract:
The presence of periprocedural conduction disorders (CDs) and the need for permanent pacemaker (PPM) after transcatheter aortic valve implantation (TAVI) are frequent findings in clinical practice. Notwithstanding, robust information on the prognostic and therapeutic implications of these complications are lacking. The newly occurrence of CD after TAVI seems related to the trauma of the conduction system during procedure. On the contrary, major predictors for PPM implantation after TAVI seem to be the use of CoreValve prosthesis (Medtronic, Minneapolis, MN) and the presence of CD before TAVI. An accurate pre-TAVI screening, careful valve implantation, as well as post-TAVI monitoring must be pursued to prevent avoidable PPM implantation. The aim of this report is to analyze the available data on this field and to propose some practical clinical tips to prevent or to manage these complications.
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