Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Chronic Obstructive Pulmonary Disease-V: Management

Chronic Obstructive Pulmonary Disease-V: Management

Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation

COPD: Management Using Bronchodilators and Corticosteroids

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...

Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...

COPD: Pathogenesis and Clinical Features

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.

Chronic Obstructive Pulmonary Disease-V: Nursing Management

Chronic Obstructive Pulmonary Disease-V: Nursing Management

Nursing management of Chronic Obstructive Pulmonary Disease (COPD) is crucial for providing thorough care and support to patients. Nurses play an integral role in this process through detailed assessment, careful planning, targeted interventions, and ongoing evaluation. Here's an overview of the critical steps in nursing management for COPD.
Assessment

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Long-term non-invasive ventilation for COPD patients following an exacerbation with acute hypercapnic respiratory failure: a randomized controlled trial.

European clinical respiratory journal·2023

Same author

Medication-assisted quit rates in participants with smoking-related diseases in EAGLES: Post hoc analyses of a double-blind, randomized, placebo-controlled clinical trial.

Tobacco induced diseases·2022

Same author

TOB-STOP-COP (TOBacco STOP in COPd trial): study protocol-a randomized open-label, superiority, multicenter, two-arm intervention study of the effect of "high-intensity" vs. "low-intensity" smoking cessation intervention in active smokers with chronic obstructive pulmonary disease.

Trials·2020

Same author

Ugeskrift for laeger·2020

Same author

Secular trends in smoking in relation to prevalent and incident smoking-related disease: A prospective population-based study.

Tobacco induced diseases·2019

Same author

Sleep Apnea, the Risk of Developing Heart Failure, and Potential Benefits of Continuous Positive Airway Pressure (CPAP) Therapy.

Journal of the American Heart Association·2018

Same journal

Implementing acute exacerbations of COPD care bundles: evidence, effectiveness and future directions.

European respiratory review : an official journal of the European Respiratory Society·2026

Same journal

Preclinical human models of primary ciliary dyskinesia.

European respiratory review : an official journal of the European Respiratory Society·2026

Same journal

Bench evidence, bedside uncertainty: hyperoxia, mechanical ventilation and lung injury.

European respiratory review : an official journal of the European Respiratory Society·2026

Same journal

Respiratory support in paediatric patients with bronchiolitis: a systematic review and meta-analysis.

European respiratory review : an official journal of the European Respiratory Society·2026

Same journal

Air pollution-induced airway epithelial barrier dysfunction in COPD: a narrative review of mechanisms and therapeutic implications.

European respiratory review : an official journal of the European Respiratory Society·2026

Same journal

Utilising human cellular models of primary ciliary dyskinesia: a scoping review.

European respiratory review : an official journal of the European Respiratory Society·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 13, 2026

Heat-sensitive Moxibustion as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Insomnia

Heat-sensitive Moxibustion as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Insomnia

Published on: May 30, 2025

Smoking cessation and COPD.

Philip Tønnesen¹

¹Department of Pulmonary Medicine, Gentofte Hospital, Niels Andersensvej 65, Hellerup, Copenhagen, Denmark. philipt@dadlnet.dk

European Respiratory Review : an Official Journal of the European Respiratory Society

|March 5, 2013

Summary

This summary is machine-generated.

Smoking cessation is crucial for Chronic Obstructive Pulmonary Disease (COPD) management. Varenicline and Nicotine Replacement Therapy (NRT) are effective, with varenicline showing higher efficacy than NRT or bupropion SR alone.

More Related Videos

Studying Effects of Cigarette Smoke on Pseudomonas Infection in Lung Epithelial Cells

Studying Effects of Cigarette Smoke on Pseudomonas Infection in Lung Epithelial Cells

Published on: May 11, 2020

Alternative Therapy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Moving Cupping Along Meridians

Alternative Therapy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Moving Cupping Along Meridians

Published on: September 27, 2024

Related Experiment Videos

Last Updated: May 13, 2026

Heat-sensitive Moxibustion as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Insomnia

Heat-sensitive Moxibustion as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Insomnia

Published on: May 30, 2025

Studying Effects of Cigarette Smoke on Pseudomonas Infection in Lung Epithelial Cells

Studying Effects of Cigarette Smoke on Pseudomonas Infection in Lung Epithelial Cells

Published on: May 11, 2020

Alternative Therapy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Moving Cupping Along Meridians

Alternative Therapy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Moving Cupping Along Meridians

Published on: September 27, 2024

Area of Science:

Pulmonology
Addiction Medicine
Pharmacology

Background:

Smoking cessation is the most effective intervention for managing Chronic Obstructive Pulmonary Disease (COPD).
Established treatments include counseling combined with varenicline, Nicotine Replacement Therapy (NRT), or bupropion SR.
Varenicline and combination NRTs demonstrate equal efficacy, with varenicline alone being more effective than NRT or bupropion SR.

Purpose of the Study:

To evaluate the efficacy of smoking cessation interventions in patients with COPD.
To compare the effectiveness of varenicline, NRT, and bupropion SR.
To assess the impact of smoking cessation on lung function and survival in COPD patients.

Main Methods:

Review of existing studies, including the Lung Health Study involving 5,587 patients with mild COPD.
Analysis of varenicline's efficacy compared to placebo in long-term NRT users.
Assessment of a new nicotine mouth spray formulation's efficacy.

Main Results:

Repeated smoking cessation over 5 years in mild COPD patients yielded a 37% quit rate.
Long-term quitters exhibited improved lung function and survival rates.
Varenicline increased quit rates in long-term NRT users compared to placebo.

Conclusions:

Smoking cessation is paramount for halting COPD progression, enhancing survival, and reducing morbidity.
Varenicline is a highly effective smoking cessation aid, though cardiovascular and psychiatric adverse events warrant consideration.
Prioritizing smoking cessation is essential in the comprehensive treatment of COPD.