Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Scaffolds for partial meniscal replacement: an updated systematic review.

Rocco Papalia¹, Francesco Franceschi, Lorenzo Diaz Balzani

¹Department of Orthopaedic and Trauma Surgery, Campus Biomedico University of Rome, Via Alvaro del Portillo 200, Rome, Italy.

British Medical Bulletin

|March 5, 2013

Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Predictors and Clinical Impact of Positive Blood Cultures in Emergency Department Patients with Suspected Infection.

Medicina (Kaunas, Lithuania)·2026

Same author

Vitamin D at hospital admission as an independent predictor of outcome of sepsis patients: Results of a secondary analysis from a "Need-Speed" trial prospective cohort.

European journal of internal medicine·2026

Same author

The Gut Microbiota: A Functional Hub Linking Nutrition, Immunity, and Cardiovascular Health.

Reviews on recent clinical trials·2026

Same author

Early Prediction of Sepsis-Related Coagulopathy: A Comparative Evaluation of Clinical Scoring Systems in the Emergency Department.

Journal of clinical medicine·2026

Same author

Cementoplasty as an effective surgical strategy for reverse shoulder arthroplasty with contained tuberosity bone loss: clinical midterm outcomes.

Journal of shoulder and elbow arthroplasty·2026

Same author

Early Sepsis Diagnosis as a Global Imperative: The Role of Raman Spectroscopy.

Journal of clinical medicine·2026

Partial meniscal replacement using scaffolds shows promising clinical results. Further high-quality randomized trials are needed to confirm these findings for osteoarthritis prevention.

Area of Science:

Orthopaedic surgery
Biomaterials science
Regenerative medicine

Background:

Meniscectomy, a common procedure, can lead to early osteoarthritis due to altered joint biomechanics.
Partial meniscal replacement aims to restore joint function and prevent osteoarthritis progression.

Purpose of the Study:

To systematically review clinical outcomes of partial meniscal replacement using various scaffolds.
To assess the efficacy and safety of different scaffold types in meniscal repair.

Main Methods:

Comprehensive literature search across major databases (Medline, CINAHL, Embase, Cochrane).
Inclusion of studies reporting clinical outcomes in patients undergoing partial meniscal replacement with scaffolds.
Methodological quality assessment using the Coleman Methodology Score (CMS).

Keywords:

collagen meniscal implant partial meniscal replacement subtotal meniscectomy synthetic meniscal scaffold

Related Experiment Videos

Main Results:

Fifteen prospective studies were included; 12 used biological scaffolds, 2 synthetic, and 1 used both.
The mean modified CMS was 64.6, indicating moderate methodological quality.
Partial meniscal replacement demonstrated significant clinical improvements compared to baseline or controls, with no device-related adverse events.

Conclusions:

Partial meniscal replacement with both biological and synthetic scaffolds yields encouraging clinical outcomes.
The procedure appears safe, with no reported adverse reactions linked to the scaffolds.
High-quality randomized controlled trials are essential to strengthen the evidence base for this treatment modality.