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Updated: May 13, 2026
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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
[Lymph node micrometastases in gastric cancer]
Takashi Fujimura1, Tomoya Tsukada, Jun Kinoshita
1Gastroenterologic Surgery, Kanazawa University, Kanazawa, Japan.
Nihon Geka Gakkai Zasshi
|March 6, 2013
Summary
Detecting lymph node micrometastases in gastric cancer intraoperatively is feasible with rapid molecular techniques. This aids surgical decisions, but the prognostic impact of micrometastases after complete resection requires further investigation.
Area of Science:
- Oncology
- Pathology
- Molecular Biology
Context:
- Lymph node micrometastases are defined by the TNM classification and Japanese Gastric Carcinoma Classification.
- Current detection methods include immunohistochemistry and molecular techniques like RT-PCR.
- Intraoperative detection is now feasible due to shortened analysis times (30-40 min).
Purpose:
- To explore the feasibility and implications of intraoperative lymph node micrometastasis detection in gastric cancer.
- To highlight the role of rapid molecular techniques in surgical decision-making.
- To address the unknown prognostic significance of micrometastases post-complete resection.
Summary:
- Gastric cancer lymph node micrometastases are defined by established classifications.
- Rapid molecular techniques enable intraoperative detection within 30-40 minutes.
- The correlation between micrometastases and prognosis, especially after complete resection, remains an area for further study.
Impact:
- Intraoperative detection of micrometastases can guide surgical procedures, particularly in sentinel node navigation surgery.
- Establishes the potential for real-time pathological assessment during surgery.
- Informs future research on the clinical significance of micrometastases in gastric cancer prognosis.
