Spontaneous regression of amiodarone pulmonary toxicity

Two patients with Amiodarone-induced interstitial lung disease are described. The pulmonary lung biopsy in one of them, as well as Chest X ray, BAL cellularity and pulmonary function data in both, are in agreement with the reports from the literature, while Ga lung scan was negative in one of the two, and positive in the other one. In both, a total resolution was seen six and four months respectively after discontinuation of Amiodarone therapy. Corticosteroid therapy could be advisable only when no spontaneous resolution occurs after tapering the drug.