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Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor (LATS) Biosensor
07:16

Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor (LATS) Biosensor

Published on: September 13, 2018

PML Surfs into HIPPO Tumor Suppressor Pathway.

Sabrina Strano1, Francesca Fausti, Silvia Di Agostino

  • 1Molecular Chemoprevention Group, Molecular Medicine Area, Regina Elena National Cancer Institute Rome, Italy.

Frontiers in Oncology
|March 6, 2013
PubMed
Summary

Promyelocytic leukemia protein (PML) enhances tumor suppression by integrating with HIPPO and p53 pathways. This crosstalk network amplifies the anti-tumor response against various oncogenic insults.

Keywords:
interactionpathwaysignalingtranscriptiontumor suppression

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