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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
Global epidemiology of tuberculosis
Philippe Glaziou1, Dennis Falzon, Katherine Floyd
1Stop TB Department (STB), HIV/AIDS, TB, Malaria and Neglected Tropical Diseases Cluster (HTM), World Health Organization, Geneva, Switzerland. glazioup@who.int
Tuberculosis (TB) remains a major global health threat, causing millions of deaths and new cases annually. This study assesses progress towards TB reduction targets and explores future elimination prospects.
Area of Science:
- * Epidemiology
- * Global Health
- * Infectious Disease Control
Background:
- * Tuberculosis (TB) caused 1.4 million deaths and 8.7 million new cases in 2011, highlighting its status as a significant global health challenge.
- * International targets for TB reduction were established for 2015 and 2050, linked to the Millennium Development Goals (MDGs) and the Stop TB Partnership.
- * Monitoring progress towards these targets is crucial for informing future public health investments and interventions.
Purpose of the Study:
- * To present methods for estimating the global burden of tuberculosis.
- * To assess progress made towards the 2015 TB reduction targets using 2011 data and trends since 1990.
- * To analyze trends in TB notifications, the implementation of the Stop TB Strategy, and the long-term outlook for TB elimination by 2050.
Main Methods:
- * Estimation of global TB incidence, prevalence, and mortality for the year 2011.
- * Trend analysis of TB indicators from 1990 to 2015 projections.
- * Evaluation of TB notification data and Stop TB Strategy implementation.
Main Results:
- * Detailed estimates of the global TB burden for 2011, including incidence, prevalence, and mortality.
- * Assessment of the progress towards achieving the 2015 global TB reduction targets.
- * Analysis of trends in TB control efforts and strategic implementation.
Conclusions:
- * The global burden of tuberculosis remains substantial, necessitating continued and intensified control efforts.
- * Progress towards the 2015 targets requires ongoing monitoring and strategic adjustments.
- * Achieving long-term TB elimination by 2050 is a complex but potentially attainable goal contingent on sustained global commitment.
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