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Counterpoint: should epidermal growth factor receptor mutations be routinely tested for in patients with lung cancer?

David C L Lam1

  • 1Department of Medicine, University of Hong Kong, Hong Kong, SAR, China.

Chest
|March 6, 2013
PubMed
Abstract

No abstract available in PubMed .

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Mitogens and their receptors play a crucial role in controlling the progression of the cell cycle. However, the loss of mitogenic control over cell division leads to tumor formation. Therefore, mitogens and mitogen receptors play an important role in cancer research. For instance, the epidermal growth factor (EGF) - a type of mitogen and its transmembrane receptor (EGFR), decides the fate of the cell's proliferation. When EGF binds to EGFR, a member of the ErbB family of tyrosine kinase...

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