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Updated: May 13, 2026

Induction of an Isoelectric Brain State to Investigate the Impact of Endogenous Synaptic Activity on Neuronal Excitability In Vivo
Published on: March 31, 2016
Brainstem excitability is not influenced by blood lactate levels
Marinella Coco1, Giovanna Alagona, Valentina Perciavalle
1Department of Biomedical Sciences, Section of Physiology, University of Catania, Catania, Italy.
Abstract:
The influence of blood lactate on brainstem excitability was tested by using the blink reflex (BR) recovery cycle on 18 sprinters. Blood lactate was measured before maximal cycling, at the end, as well as 5 and 10 min after the exhaustion. Blood lactate was associated with a decrement of R2 whereas only small changes were observed after an intravenous infusion of lactate. It seems, therefore, that lactate influences BR mainly by acting at the cortical level.
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