Related Experiment Video

Updated: May 13, 2026

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
04:40

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans

Published on: August 28, 2018

Coronary artery calcification and ECG pattern of left ventricular hypertrophy or strain identify different healthy

Søren Zöga Diederichsen1, Oke Gerke, Michael Hecht Olsen

  • 1Department of Cardiology, Odense University Hospital, Odense, Denmark.

Journal of Hypertension
|March 7, 2013
PubMed

Insights

Coronary artery calcification (CAC) and ECG findings of left ventricular hypertrophy/strain do not appear related. These markers may identify different individuals at risk for ischaemic heart disease and offer additive prognostic value.

Area of Science:

  • Cardiology
  • Preventive Medicine
  • Diagnostic Imaging

Background:

  • Ischaemic heart disease risk stratification benefits from multiple markers.
  • Coronary artery calcification (CAC) and ECG patterns of left ventricular hypertrophy (LVH)/strain provide independent prognostic information.

Purpose of the Study:

  • Investigate the association between established risk factors, ECG measurements, and the presence of CAC.
  • Evaluate the relationship between ECG-suspected LVH/strain and CAC.

Main Methods:

  • A random sample of 1226 healthy individuals aged 50 or 60 years underwent screening.
  • CAC score assessed via noncontrast computed tomographic (CT) scan.
  • ECG analysis included LVH (Sokolow-Lyon, Cornell product) and strain patterns; multivariate logistic regression used for association analysis.

Main Results:

  • Hypertension prevalence was 50%.
  • Hypertensive individuals showed higher rates of LVH/strain (21% vs. 14%) and CAC (52% vs. 38%) compared to non-hypertensives.
  • No association was found between ECG abnormalities (LVH/strain) and the presence of CAC in multivariate analyses.

Conclusions:

  • No relationship exists between CAC and ECG-suspected LVH and/or strain.
  • CAC and ECG findings may identify distinct individuals at risk.
  • Combined use of these markers could offer additive prognostic value for ischaemic heart disease.
Abstract

More Related Videos

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography06:34

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Electrocardiogram01:29

Electrocardiogram

An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and the T...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...