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Updated: May 13, 2026
07:56
Rectal Organoid Morphology Analysis (ROMA): A Diagnostic Assay in Cystic Fibrosis
Published on: June 10, 2022
Anomalies associated with anorectal malformations.
R N Bălănescu1, L Topor, A Moga
1Department of Pediatric Surgery, "Grigore Alexandrescu" Emergency Clinical Hospital for Children, Bucharest, Romania.
Chirurgia (Bucharest, Romania : 1990)
|March 8, 2013
Summary
This study found that 68% of newborns with anorectal malformations (ARM) have associated congenital anomalies, most commonly gastrointestinal defects. These findings highlight the importance of comprehensive screening for comorbidities in ARM patients.
Area of Science:
- Pediatric Surgery
- Congenital Abnormalities
- Neonatal Care
Background:
- Anorectal malformations (ARM) are complex congenital conditions.
- Associated anomalies are common in ARM patients, impacting management and outcomes.
- Understanding the spectrum of these comorbidities is crucial for clinical practice.
Purpose of the Study:
- To determine the incidence of congenital anomalies associated with anorectal malformations.
- To compare these findings with existing published data.
- To identify patterns of anomalies based on ARM type.
Main Methods:
- Retrospective review of 50 patients with ARM (2005-2012).
- Data collection included patient demographics, ARM type, and associated anomalies.
- Associated anomalies were categorized by organ system.
Main Results:
- 68% of 50 newborns with ARM had at least one associated anomaly.
- Most frequent anomalies: gastrointestinal (36%), urogenital (24%), and cardiovascular (16%).
- Imperforate anus without fistula was the most common ARM type (40%).
Conclusions:
- Gastrointestinal anomalies are the most frequent comorbidities in ARM.
- Higher incidence of GI anomalies in persistent cloacal anomaly.
- Rectovestibular fistula associated with cardiac anomalies; perineal fistula with genitourinary anomalies.
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