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Related Concept Videos

Uterus and Cervix01:18

Uterus and Cervix

The uterus, commonly called the womb, is a vital reproductive organ in females designed to provide a nurturing environment for the implantation and growth of an embryo. It is shaped like a hollow pear and positioned between the urinary bladder and the rectum. The uterus's structure allows it to support and protect a developing fetus throughout pregnancy.
The uterus is securely anchored within the pelvic cavity by paired broad ligaments on either side. It is further stabilized by three pairs of...
Uterine Tubes01:16

Uterine Tubes

The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...
Histology of the Uterus01:19

Histology of the Uterus

The uterine wall consists of three histological layers: the perimetrium, myometrium, and endometrium. The outermost perimetrium is a thin, serous membrane connected with the broad ligament on the sides, which helps anchor the uterus in the pelvic cavity. The thickest layer, myometrium, is mainly made up of smooth muscle tissue bundles. Its contractions are vital in facilitating the expulsion of the uterine lining, fetus, and placenta during menstruation and childbirth.
The endometrium is the...

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Related Experiment Video

Updated: May 13, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
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Large uterine neurofibroma.

Shailesh Ernest Gokavi1, Ravikumar Jadhav, Purushotham Reddy

  • 1Centre for Fertility Care and Laparoscopic Surgery, Near Basel Mission Church, Hubli, Karnataka, India. segokavi@yahoo.com

Journal of Minimally Invasive Gynecology
|March 8, 2013
PubMed
Summary
This summary is machine-generated.

This report details a rare, large uterine neurofibroma causing infertility. Surgical removal confirmed the diagnosis, highlighting the rarity of such deep-tissue tumors.

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Area of Science:

  • Gynecologic Oncology
  • Surgical Pathology
  • Reproductive Medicine

Background:

  • Uterine neurofibromas are uncommon neoplasms.
  • They can present with nonspecific pelvic symptoms and infertility.
  • Distinguishing them from uterine myomas preoperatively can be challenging.

Observation:

  • A large uterine mass (13 × 9 × 8 cm) was identified in a patient with infertility.
  • Initial imaging suggested a uterine myoma.
  • The mass originated from the uterine fundus and extended into the broad ligament.

Findings:

  • Laparoscopic myomectomy was performed.
  • Histopathologic examination and immunohistochemistry confirmed a uterine neurofibroma.
  • This represents a rare instance of a large, deep-tissue neurofibroma of the myometrium.

Implications:

  • Large uterine neurofibromas are rare and require accurate diagnosis.
  • Deep-tissue neurofibromas have a potential for recurrence and malignant transformation.
  • Awareness of this rare entity is crucial for appropriate patient management and follow-up.