Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dissociable somatotopic representations of Chinese action verbs in the motor and premotor cortex.

Scientific reports·2013
Same author

High quantum-yield CdSexS1-x/ZnS core/shell quantum dots for warm white light-emitting diodes with good color rendering.

Nanotechnology·2013
Same author

Osteopontin mediating cyclosporine A induced epithelial-to-mesenchymal transition on rat renal tubular epithelial cells.

Cell biology international·2013
Same author

A novel microfluidic mixer based on dual-hydrodynamic focusing for interrogating the kinetics of DNA-protein interaction.

The Analyst·2013
Same author

Correlation of reorientational jumps of water molecules in bulk water.

Physical review. E, Statistical, nonlinear, and soft matter physics·2013
Same author

Palladium-catalyzed direct arylation of C-H bond to construct quaternary carbon centers: the synthesis of diarylfluorene.

Organic letters·2013
Same journal

Oral colon-targeted micro-nano formulation engineered in microfluid for synergistic therapy of inflammatory bowel disease.

Biomaterials·2026
Same journal

Manganese@Gold cluster-coordinated covalent organic frameworks-based artificial metalloenzymes with cascade biocatalysis and amplified systemic stimulation to combat malignant tumor metastasis.

Biomaterials·2026
Same journal

Remodeling TME via feedback-driven photothermal-ferroptosis-immune cascade.

Biomaterials·2026
Same journal

Corrigendum to "Photodynamic therapy produces enhanced efficacy of antitumor immunotherapy by simultaneously inducing intratumoral release of sorafenib" [Biomaterials 2020, 240, 119845].

Biomaterials·2026
Same journal

Mg-integrated octopus-inspired hydrogel dressing enables autonomous adhesion and wound closure for enhanced healing via sequential microenvironment regulation.

Biomaterials·2026
Same journal

Engineering miRNA-223 nanocomplexes via bioorthogonal self-assembly for precision therapy of intervertebral disc degeneration.

Biomaterials·2026
See all related articles

Related Experiment Video

Updated: May 13, 2026

Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures
13:38

Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures

Published on: April 11, 2017

Fluorescence imaging enabled urethane-doped citrate-based biodegradable elastomers.

Yi Zhang1, Richard T Tran2, Ibrahim S Qattan1

  • 1Department of Bioengineering, The University of Texas at Arlington, Arlington, TX 76010, USA.

Biomaterials
|March 8, 2013
PubMed
Summary
This summary is machine-generated.

Researchers developed urethane-doped biodegradable photoluminescent polymers (UBPLPs) for tissue engineering and drug delivery. These novel materials exhibit strong photoluminescence, excellent mechanical properties, and potential for non-invasive in vivo bioimaging.

More Related Videos

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro
10:01

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro

Published on: April 8, 2020

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
11:49

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

Published on: March 8, 2019

Related Experiment Videos

Last Updated: May 13, 2026

Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures
13:38

Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures

Published on: April 11, 2017

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro
10:01

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro

Published on: April 8, 2020

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
11:49

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

Published on: March 8, 2019

Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Tissue Engineering
  • Drug Delivery

Background:

  • The fields of tissue engineering and drug delivery require advanced measurement tools and non-invasive assays.
  • Previous work established intrinsically biodegradable photoluminescent polymers (BPLPs).

Purpose of the Study:

  • To develop a new type of urethane-doped biodegradable photoluminescent polymers (UBPLPs) for tissue engineering and drug delivery applications.
  • To evaluate the photoluminescence, mechanical properties, and in vitro/in vivo performance of UBPLPs.

Main Methods:

  • Synthesis of urethane-doped biodegradable photoluminescent polymers (UBPLPs).
  • Characterization of crosslinked UBPLPs (CUBPLPs) for mechanical properties (tensile strength, elongation at break).
  • Fabrication and testing of porous triphasic CUBPLP vascular scaffolds (burst pressure, suture retention).
  • Preparation of UBPLP nanoparticles via nanoprecipitation for drug delivery studies.
  • Evaluation of drug loading efficiency and sustained release of 5-fluorouracil.
  • Assessment of photoluminescence quantum yield and in vivo non-invasive detection capabilities.

Main Results:

  • UBPLPs demonstrated strong inherent photoluminescence and excellent cytocompatibility in vitro.
  • CUBPLPs exhibited robust mechanical properties: tensile strength of 49.41 ± 6.17 MPa and elongation at break of 334.87 ± 26.31%.
  • Porous triphasic CUBPLP scaffolds showed high burst pressure (769.33 ± 70.88 mmHg) and suture retention strength (1.79 ± 0.11 N).
  • UBPLP nanoparticles (103 nm) achieved high drug loading (91.84%) and sustained release of 5-fluorouracil for up to 120 hours.
  • A high quantum yield (38.65%) enabled non-invasive in vivo detection of both scaffolds and nanoparticles.

Conclusions:

  • UBPLPs represent a significant innovation in fluorescent biomaterial design.
  • These materials offer great potential for advancing tissue engineering and drug delivery through enhanced bioimaging capabilities.
  • The developed UBPLPs can serve as versatile tools for non-invasive monitoring and therapeutic applications.