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Orthotopic Hind Limb Transplantation in the Mouse
Published on: February 12, 2016
Cross-over limb replantation: a case report
W J M Holmes1, A Williams, K J M Everitt
1Department of Hand and Plastic Surgery, Leeds General Infirmary, Great George Street, Leeds LS1 0UX, United Kingdom. willjmholmes@googlemail.com
Summary
A rare cross-limb forearm replantation in a woman with bilateral arm amputation restored significant function. This procedure offered superior independence compared to a prosthesis, highlighting its potential in similar complex cases.
Area of Science:
- Reconstructive surgery
- Microsurgery
- Trauma surgery
Background:
- Bilateral arm amputation presents significant challenges for functional restoration.
- Orthotopic replantation is not always feasible in severe traumatic amputations.
Observation:
- A 46-year-old woman with traumatic bilateral arm amputation underwent a left forearm replantation to the right proximal forearm.
- Two-year follow-up demonstrated a sensate hand with functional recovery of flexors and extensors.
Findings:
- The patient achieved a high level of function, outperforming her contralateral prosthetic limb.
- The DASH score was 93.9 and Chen's score was III, indicating medium functional recovery.
Implications:
- Cross-limb replantation can provide superior function and independence compared to prosthetics in specific amputation scenarios.
- This rare procedure should be considered when orthotopic replantation is impossible for both arms.
Keywords:
AmputationCross-over limbHandLimb salvageOrthotopic transplantationReplantationTransplant rehabilitation