Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Mechanical Ventilation II: Invasive Ventilation

Mechanical Ventilation II: Invasive Ventilation

Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...

Burn Injuries

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...

Pneumonia III: Complications and Assessment

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:

Pneumonia V: Nursing management and Prevention

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.

Acute Respiratory Failure-V

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...

Mechanical Ventilation III: Noninvasive Ventilation

Mechanical Ventilation III: Noninvasive Ventilation

Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation (NIPPV)

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Evaluating First Positive Cultures in Burns: Rethinking Broad-Spectrum Antibiotic Choices.

Journal of burn care & research : official publication of the American Burn Association·2025

Same author

Professor Jan H Louw: South Africa's paediatric surgery pioneer.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2025

Same author

Paediatric ambulant burn care treatment in a tertiary burn unit.

South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie·2025

Same author

Complex Regional Pain Syndrome Following Minor Burns: A Rare but Significant Complication.

Journal of burn care & research : official publication of the American Burn Association·2025

Same author

Investigating the Role of Amazonian Mesoscale Wind Patterns and Strength on the Spatial Distribution of Martian Bedrock Exposures.

Journal of geophysical research. Planets·2023

Same author

Delayed axial flaps for coverage of a fourth degree scalp burn.

Journal of surgical case reports·2022

Search research articles

Related Experiment Video

Updated: May 13, 2026

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds

Published on: February 23, 2024

Review article: ventilator-associated pneumonia in major burns.

A D Rogers¹, A C Argent, H Rode

¹Division of Plastic Surgery.

Annals of Burns and Fire Disasters

|March 8, 2013

Summary

Major burn patients face high risks of ventilator-associated pneumonia (VAP). Early diagnosis and treatment, alongside preventative strategies, are crucial for managing this severe complication in burn care.

Keywords:

major burn injuries mechanical ventilation mortality and morbidity in burns nosocomial infections ventilator associated pneumonia

More Related Videos

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia

Published on: June 28, 2018

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment

Published on: November 6, 2018

Related Experiment Videos

Last Updated: May 13, 2026

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds

Published on: February 23, 2024

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia

Published on: June 28, 2018

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment

Published on: November 6, 2018

Area of Science:

Critical Care Medicine
Infectious Diseases
Burn Surgery

Background:

Ventilator-associated pneumonia (VAP) is a significant cause of death and illness in major burn patients.
Despite advances in intensive care and surgery, VAP incidence remains high.

Purpose of the Study:

To highlight the risk factors and management strategies for VAP in major burn victims.
To emphasize the importance of early diagnosis and treatment protocols for VAP.

Main Methods:

Review of existing literature on VAP in burn patients.
Analysis of risk factors including ventilation duration, burn characteristics (type, size, inhalation injury), re-intubations, and theatre visits.
Discussion of diagnostic approaches including clinical criteria, radiology, and broncho-alveolar lavage.
Emphasis on early empiric therapy based on local resistance patterns.

Main Results:

Ventilation duration, burn severity (especially inhalational burns), re-intubations, and theatre visits are key risk factors for VAP.
Effective prevention and timely, targeted treatment are essential for improving outcomes.
Multidisciplinary care in specialized centers is recommended for optimal management.

Conclusions:

VAP poses a substantial threat to major burn survivors, necessitating vigilant management.
Adherence to preventative measures and prompt, evidence-based treatment protocols are critical.
Centralized care in specialized burn units with comprehensive resources improves patient outcomes.