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Updated: May 13, 2026

Mouse Complete Stasis Model of Inferior Vena Cava Thrombosis
Published on: June 15, 2011
Release of the inferior vena cava ligament during caval thrombectomy causing tumor thrombus embolization
Shivam Joshi1, Michael A Gorin, Gaetano Ciancio
1Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL 33101, USA.
Abstract:
Intraoperative tumor embolization is a rare complication during the surgical management of renal cell carcinoma with tumor thrombus of the inferior vena cava (IVC). We present a case of pulmonary tumor embolism which occurred during liver mobilization immediately following division of the IVC ligament. We hypothesize that this patient's IVC ligament acted as an external barrier to propagation of the tumor thrombus and that its release caused the tumor to rapidly expand leading to embolization. To our knowledge, this is the first report of a pulmonary tumor embolism occurring immediately following division of the IVC ligament.
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